Results 91 to 100 of about 377,869 (311)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Living donor liver transplantation [PDF]
British Journal of Surgery, 2005 S A, White, S G, Pollard
+7 more sources
Effectiveness of Different Kidney Exchange Mechanisms on Improving Living Donor Transplantation in Chile [PDF]
Chile has a very low cadaveric organ donation rate; at the same time, living donor transplantation activity is low. The purpose of this paper is to analyze the impact on the number and quality of transplants of the potential application of different ...
Diego Contreras, Javier Dominguez
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India Giving: Insights into the Nature of Giving Across India [PDF]
, 2012 Giving in India is as ancient as the country itself. The instinct to give is part of the ebb and flow of our daily lives, permeating our religions, our culture and our history.
Richard Harrison, Terrie Maple
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
De Behoefte aan Psychosociale Steun bij Deelnemers aan het Nederlandse Cross-over Transplantatie Programma [PDF]
, 2006 Final technical report of the project.The Dutch kidney exchange donation program started in January 2004. A literature review has shown that several factors of the exchange program could influence the psychological well being of participants, such as the
Busschbach, J.J. (Jan) van +7 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Addressing Kidney Transplant Shortage: The Potential of Kidney Paired Exchanges in Jordan
Journal of TransplantationJordan performed the Middle East’s first living-donor kidney transplant in 1972. In 1977, the country became one of the first Arab countries to regulate organ donation and transplantation.
Mohammad H. Al-Thnaibat +8 more
doaj +1 more source
Hyperuricaemia in cyclosporin-treated patients: a GFR-related effect [PDF]
, 2017 Background Hyperuricaemia is a well known side-effect of cyclosporin A (CsA) treatment. The pathogenic mechanisms, however, remain controversial. There is no convincing evidence that hyperuricaemia is due to CsA-induced, impaired tubular handling of uric
Bock, H. A., Thiel, G., Zürcher, R. M.
core
The relevance of EU directive 2010/53/EU for living organ donation practice [PDF]
, 2016 With the recent transposition of Directive 2010/53/EU into the transplant regulation of EU Member States, the time is right to have a closer look at its implications for living organ donation practice.
Burnapp, Lisa +10 more
core +1 more source