Results 131 to 140 of about 2,279,811 (306)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Sequential dual-organ living donation: selection, operative approach, and early donor outcomes at a Canadian center

Transplant International
Sequential dual-organ living donation, defined as donation of a kidney and a partial liver graft by the same individual in separate operations, represents a rare extension of living donor transplantation.
Su Kah Goh, Nazia Selzner, Nazia Selzner, Sunita K. Singh, Sunita K. Singh, Ian D. McGilvray, Ian D. McGilvray, Chaya Shwaartz, Chaya Shwaartz, Trevor W. Reichman, Trevor W. Reichman, Nicolas Goldaracena, Nicolas Goldaracena, Nicolas Goldaracena, Jason Y. Lee, Jason Y. Lee, Markus Selzner, Markus Selzner, Gonzalo Sapisochin, Blayne Amir Sayed, Blayne Amir Sayed, Blayne Amir Sayed, Mark S. Cattral, Mark S. Cattral, Anand Ghanekar, Anand Ghanekar   +25 more
doaj   +1 more source

Impact of extended living donor criteria on donor safety in living donor liver transplantation

Korean Journal of Transplantation, 2020
Joo Dong Kim, Donglak Choi, Eunkyoung Jwa   +2 more
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Predictors of decision ambivalence and the differences between actual living liver donors and potential living liver donors

, 2018
[[abstract]]Abstract Background The decision to become a living liver donor is a stressful event. Ambivalence in decision making may result in psychological distress.
Weng, Li-Chueh;Huang, Hsiu-Li;Tsai, Hsiu-Hsin;Lee, Wei-Chen
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Living Donors' Age Modifies the Impact of Pre-Donation Estimated Glomerular Filtration Rate on Graft Survival. [PDF]

J Clin Med, 2023
Almeida M, Ribeiro C, Silvano J, Pedroso S, Tafulo S, Martins S, Ramos M, Malheiro J.   +7 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Psychological evaluation of living liver donors--a single centre experience

, 2010
The psychological evaluation of living liver donors is a substantial part of the preoperative evaluation of donors in many transplantation centres around the globe and aims at securing decision autonomy and informed consent, verifying the psychological ...
Papachristou, C., Klapp, B. F., Walter, M.   +2 more
core