Results 161 to 170 of about 377,869 (311)

Living donors: con. [PDF]

, 1987
Starzl, TE
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Impact of Type 1 Diabetes on Endothelial Cells Derived From Living Donors. [PDF]

FASEB Bioadv
Marei I, Vinokurova M, Qiucheng L, Nyhegn L, Dubuis E, Baig A, Mohamed N, Rothery S, Kirkby NS, Salem V, Oliver N, Mitchell JA, Ahmetaj-Shala B.   +12 more
europepmc   +1 more source

The advantage of early liver transplantation for Wilson's disease using living donors. [PDF]

Prz Gastroenterol, 2021
Dal MB, Alim A, Acarli K.
europepmc   +1 more source

Cadaveric vs. Live-Donor Kidney Transplants: The Interaction of Institutions and Inequality [PDF]

In 1991, the World Health Assembly approved a set of Guiding Principles which emphasize voluntary donation, non-commercialization and a preference for cadavers over living donors” (World Health Organization).
Mustafa Caglayan, Nejat Anbarci
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Impact of the preoperative skeletal muscle index on early remnant liver regeneration in living donors after liver transplantation. [PDF]

Korean J Transplant, 2022
Lee S, Kim KW, Kwon HJ, Lee J, Song GW, Lee SG.   +5 more
europepmc   +1 more source

Kidney Transplant Program Offers Many Options and Encourages Living Donors [PDF]

, 2010

core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Successful forearm and hand transplantations from living donors: the first report. [PDF]

Int J Surg
The-Hoang N, Ngoc-Huyen N, Ba-Minh N, Quang-Vinh N, Nuwayhid R, Viet-Nam N, Thai-Hung N, Le H, Hong-Bang M.   +8 more
europepmc   +1 more source