Results 191 to 200 of about 377,869 (311)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Living donors kidney transplantation and oxidative stress: Nitric oxide as a predictive marker of graft function. [PDF]

PLoS One
Izemrane D, Benziane A, Makrelouf M, Hamdis N, Rabia SH, Boudjellaba S, Baz A, Benaziza D.   +7 more
europepmc   +1 more source

Usability assessment of an interactive health technology for kidney living donors: protocol for a prospective cross-sectional survey. [PDF]

BMJ Open, 2022
Ortiz F, Giunti G.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Didactical characteristics of Dutch websites about kidney transplantation targeted for kidney patients and living donors: An exploratory study. [PDF]

PEC Innov, 2022
van Klaveren CW, de Jong PGM, Hendriks RA, Luk F, de Vries APJ, van der Boog PJM, Rabelink AJ, Reinders MEJ.   +7 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Comparison of Kidney Graft Function and Survival in an Emulated Trial With Living Donors and Brain-Dead Donors. [PDF]

Transpl Int
Savoye E, Santin G, Legeai C, Kerbaul F, Gaillard F, Pastural M.   +5 more
europepmc   +1 more source

Understanding Risks and Our Responsibility to Living Donors.

J Am Soc Nephrol, 2021
Gill JS, Schold J, Kaplan B.
europepmc   +1 more source

Imaging evaluation of uterine arteries in potential living donors for uterus transplantation: a comparative study of MRA, CTA, and DSA. [PDF]

Eur Radiol, 2022
Leonhardt H, Thilander-Klang A, Båth J, Johannesson M, Kvarnström N, Dahm-Kähler P, Brännström M.   +6 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source