Results 171 to 180 of about 802,900 (310)

NASA Decadal Astrobiology Research and Exploration Strategy (NASA-DARES 2025) White Paper -- Habitable Worlds Observatory Living Worlds Science Cases: Research Gaps and Needs [PDF]

open access: green
Scott M. Perl   +30 more
openalex   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Discriminatory attitudes toward people living with HIV/AIDS in East Africa: a multilevel analysis of socioeconomic and behavioral determinants using DHS 2019-2023 data. [PDF]

open access: yesAIDS Res Ther
Kibralew G   +14 more
europepmc   +1 more source

Vulnerability and non-adherence to antiretroviral treatment in women living with HIV (Web of Science).

open access: gold
Denise Eliziana de Souza   +2 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Direct Observation of Nanometer-Sized Steps of Single Myosin VI Molecules in Living Cells. [PDF]

open access: yesNano Lett
Nguyen QQ   +7 more
europepmc   +1 more source

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