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Principles for the design of multicellular engineered living systems [PDF]
Onur Aydin +16 more
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Mitochondria produce high amounts of ATP to power myosin motors and sustained muscle contraction. Here, the authors show that during development, muscles coordinate the morphogenesis of their myofibrils directly with their mitochondria to optimize both ...
Jerome Avellaneda +6 more
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Today, more than ever, the search for non-trivial sources of biologically active substances is critical. Plants of the genus Rumex are noteworthy.
Pavel Feduraev +10 more
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Desmosomal connectomics of all somatic muscles in an annelid larva
Cells form networks in animal tissues through synaptic, chemical, and adhesive links. Invertebrate muscle cells often connect to other cells through desmosomes, adhesive junctions anchored by intermediate filaments.
Sanja Jasek +6 more
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Serotonin is a neurotransmitter that signals through 5-HT receptors to control key functions in the nervous system. Serotonin receptors are also ubiquitously expressed in various organs and have been detected in embryos of different organisms.
Sanjay Karki +7 more
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CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage
New virions of Ff bacteriophages are extruded from the host cell via the channel built from phage protein pIV, homologous to bacterial secretins. Here, the authors report the structure of this channel from the f1 filamentous bacteriophage and propose its
Rebecca Conners +9 more
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CA1 pyramidal cell diversity is rooted in the time of neurogenesis
Cellular diversity supports the computational capacity and flexibility of cortical circuits. Accordingly, principal neurons at the CA1 output node of the murine hippocampus are increasingly recognized as a heterogeneous population. Their genes, molecular
Davide Cavalieri +7 more
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In vitro reconstitution of branching microtubule nucleation
Eukaryotic cell division requires the mitotic spindle, a microtubule (MT)-based structure which accurately aligns and segregates duplicated chromosomes.
Ammarah Tariq +4 more
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Biomechanics and neural circuits for vestibular-induced fine postural control in larval zebrafish
The postural control mechanism in fish is unclear. Here, authors show that larval zebrafish recover upright posture after roll tilts by a body bend that produces corrective rotational torque. They also reveal the associated neural circuits and muscles.
Takumi Sugioka +2 more
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Natural habitats, including extreme ones, are potential sources of new antimicrobial compound producers, such as bacteriocins and enzymes, capable of degrading the matrix polysaccharides of bacterial biofilms. This study aimed to investigate biodiversity
Margarita Shevchenko +8 more
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