Results 121 to 130 of about 5,778,795 (297)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
BMC Medical EthicsBackground Understanding the treatment preferences of terminally ill patients is critical for the provision of quality care at the end of life. However, there is limited literature on the perspectives and willingness to develop advance directives among ...
Catherine Alupo +3 more
doaj +1 more source
Collective learning experiences in planning: the potential of experimental living labs [PDF]
, 2015 ‘Living labs’ originate from an R&D environment, and intend to innovate commodities by experience-based knowledge, with a direct involvement of users. Meanwhile, the living labs approach has been shifting into a wider range of applications, and has also ...
Dehaene, Michiel +2 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Fiscal Tonic for an Aging Nation: A Shadow Federal Budget for 2007 [PDF]
Saving and investment are critical to Canada's economy. They underpin today's prosperity and will be critical to raising living standards in the future.
Finn Poschmann +2 more
core
Quantifying carbon allocation to mycorrhizal fungi by temperate forest tree species across a nitrogen availability gradient [PDF]
, 2013 Terrestrial ecosystems make up the largest carbon pool with a major portion of that being forests. With carbon being a major concern due to global climate change, being able to make accurate models is increasingly important. Studies have shown that trees
Tumber-Davila, Shersingh Joseph
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
, 2017 Living in the world of clever devices, using them every hour for our needs, we can`t imagine that something can change dramatically, but it exactly will. In about 20 years we can become witnesses of a new period when the people`s work could be easier,
Dzbanovskii, Yurii +2 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
BMC NursingBackground Steeped in cultural heritage, the Chinese traditionally equate death with misfortune. This deeply rooted belief has led to a low rate of living will signings and poses challenges for implementing death education.
Yishan Yan +3 more
doaj +1 more source