Results 41 to 50 of about 1,974,145 (268)

Why have Advance Directives failed in Spain?

open access: yesBMC Medical Ethics, 2020
Background In Spain, there has been great effort by lawmakers to put Advance Directives (ADs) into practice since 2002. At the same time, the field of bioethics has been on the rise, a discipline that has spurred debate on the right of patients to ...
Benjamín Herreros   +5 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Statistics of living polymer rings [PDF]

open access: yes, 2022
Living polymers are macromolecules that can undergo several structural changes. In particular they can break and reform on experimental time scales.
Gattone, Luigi
core  

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Promotion Challenges and Response Strategies for the Living Will System in China

open access: yesYixue yu zhexue
The limited promotion of the living will system in China reflects the normative conflicts between the right to dignity of life and the right to medical autonomy.
Lvmo LI, Mengting DONG
doaj   +1 more source

Palliative Care professionals knowledge and attitudes regarding Advance Directives in Metropolitan Region, Chile

open access: yesRevista Colombiana de Bioética, 2018
Advance Directives are grounded on the principles of respect for autonomy and beneficence. They are recommended in order to facilitate better health decision-making at the end of life. In Chile, they are not legally recognised, and there
Mariana Dittborn Bellalta
doaj   +1 more source

Perspective on advanced directives among older adults in Shanghai: A qualitative study

open access: yesInternational Journal of Nursing Sciences, 2023
Objective: This study aimed to explore the perception on advanced directives (ADs) among older adults in Shanghai. Methods: Through purposive sampling, 15 older adults with rich life experiences who were willing to share perceptions and experiences of ...
Rong-Rong Zhang, Yan Xu, Yue-Ping Zhao
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Co-creation in living labs

open access: yes, 2016
© Springer International Publishing Switzerland 2017.Living Labs are places for open innovation where co-creation is a method for addressing real-life issues through the attribution of knowledge from science and society, the latter being a form of ...
Morrison, Gregory M. (R20662)   +12 more
core   +1 more source

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