Results 111 to 120 of about 638,475 (268)

RAGE Re-Expressed at Myofibre Level Drives Muscle Wasting in Cancer Conditions. [PDF]

J Cachexia Sarcopenia Muscle
Chiappalupi S, Gentili G, Salvadori L, Paiella M, Manfredi M, Borrini VF, Mangar K, Schmidt AM, Muscaritoli M, Riuzzi F, Sorci G.   +10 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

P-glycoprotein 1 as a shared target for resensitizing drug-resistant tumor cells and preventing fibronectin-driven metastasis. [PDF]

Theranostics
Huang LT, Cheng LH, Kuo CH, Cheng CY, Sheu SR, Yang CH, Shih PC, Li YS, Tseng L, Hsueh WT, Hao LJ, Cheng HC.   +11 more
europepmc   +1 more source

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

Advanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller, Nicole Vo, Utkarsh, Ivan Sokirniy, Justin Pritchard, Benjamin S. Freedman, Scott H. Medina   +6 more
wiley   +1 more source

LLC Rezonans Dönüştürücü Tasarımı

, 2019
98
openaire   +2 more sources

Internship at Watermen LLC

Journal of Science & Engineering
Civil engineering plays a critical role in the planning, construction, and maintenance of infrastructure systems that support residential and commercial development. Watermen LLC is a civil engineering and construction firm specializing in underground utilities, site development, and water and sewer infrastructure projects.
openaire   +1 more source

[Ultrasound-synergized targeted nanoparticles suppress proliferation, migration and invasion of hypoxic lung cancer cells <i>in vitro</i>]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Dong J, Guo J, Li D, DU Y.
europepmc   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

Streamlining the MRI-Derived Vertebral Bone Quality Score for Preoperative Osteoporosis and Osteopenia Screening. [PDF]

Global Spine J
Köhli P, Guven AE, Mielke AM, Alschuler DM, Lan R, Hambrecht J, Chiapparelli E, Schönnagel L, Evangelisti G, Duculan R, Shue J, Tsuchiya K, Pumberger M, Burkhard MD, Mancuso CA, Sama AA, Girardi FP, Cammisa FP, Hughes AP.   +18 more
europepmc   +1 more source

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

Advanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao, Ruqiong Wang, Bo An, Lishuang Qi, Zihan Jing, Xingmei Ren, Yang Zhou, Mingjun Xu, Jiaojiao Li, Jie Liu, Liying Wang, Gang Xu, Rou Li, Dexin Jia, Yan Yu   +14 more
wiley   +1 more source