Results 211 to 220 of about 13,515,683 (358)

Phloretin Attenuates Cancer Cachexia-Induced Skeletal Muscle Wasting Associated with the Modulation of STAT3 Signaling. [PDF]

Biomedicines
Lin K, He MW, Wang F, Hu XY, He ZY, Zhang CL, Huang ZQ, Wang HW.   +7 more
europepmc   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Calcined lotus leaf-derived carbon dots: enhanced hemostasis, anti-inflammatory, immunomodulatory properties for ulcerative colitis management. [PDF]

J Nanobiotechnology
Zheng Y, Liu J, Ma Y, Zhang Y, Liu H, Chen R.   +5 more
europepmc   +1 more source

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

Cascade-activatable small-molecule theranostic nanomicelles for photodynamic-immunotherapy of immune-cold lung tumors. [PDF]

Asian J Pharm Sci
Yoon YC, Kim HJ, Choi Y.
europepmc   +1 more source

Card from Nomacorc LLC

, 2012
Nomacorc LLC
core  

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Tumor-targeted aptamer-conjugated engineered bacteria for CXCL9 cytokine delivery in non-small cell lung cancer immunotherapy. [PDF]

J Transl Med
Gu Q, Wang R, Zhang L, Pan D, Bian C, Jia E, Chang J, Zhang H.   +7 more
europepmc   +1 more source

Amendment #1 to Hosted Services Agreement by and between ValueCentric, LLC and Actavis Kadian LLC

, 2011
ValueCentric, LLC; Actavis Kadian LLC
core  

Surface Energy Modulated Self‐Assembly of Percolative Gallium Nanodroplet Films for Stretchable Electronics

Advanced Electronic Materials, EarlyView.
Surface‐energy guided self‐assembly of liquid metals enables the transformation of liquid metal micro/nanodroplets into continuous perocolative films on elastomeric substrates. By tailoring interfacial energetics and wetting behavior, uniform, conductive, and stretchable films are achieved, offering scalable pathways for high‐performance soft ...
Alwar Samy Ramasamy, Gayatri Subhalaxmi, Sneha Banerjee, Mark Vailshery, Renu Raman Sahu, Sivakumar K.S, Ajisha Chathyattu, Tapajyoti Das Gupta   +7 more
wiley   +1 more source