Results 291 to 300 of about 1,395,480 (391)

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

High-CD14-expressing urothelial cancer cells foster a neutrophil-rich tumor microenvironment that increases the risk of radiation-promoted distant metastasis. [PDF]

J Biomed Sci
Chiang Y, Tsai YC, Wang CC, Hsueh FJ, Huang CY, Chen CH, Pu YS, Chueh SC, Tsai XC, Cheng JC.   +9 more
europepmc   +1 more source

GM-CSF Armed Oncolytic Adenovirus Enhances T-Cell Infiltration and Suppresses Local and Distal Tumor Growth. [PDF]

Viruses
Xu HW, Wang QW, Zhao M, Jun J, Shu RG, Shi YS, Peng XL, Yu JM, Zheng YP, Fu YH, He JS.   +10 more
europepmc   +1 more source

Correction: Yu et al. Non-Cationic RGD-Containing Protein Nanocarrier for Tumor-Targeted siRNA Delivery. Pharmaceutics 2021, 13, 2182. [PDF]

Pharmaceutics
Yu X, Xue L, Zhao J, Zhao S, Wu D, Liu HY.   +5 more
europepmc   +1 more source

The integrin protein ITGβ1 effectively suppresses porcine epidemic diarrhea virus replication through facilitating MDA5 oligomerization and subsequent activation of the type I interferon signaling pathway. [PDF]

J Virol
Yu J, Sun Q, Zhu J, Cui Y, Chen P, Shen W, Yue Y, Jiang Y, Liu C, Liu H, Tong G, Gao F, Zhou Y.   +12 more
europepmc   +1 more source

Trenton Biogas LLC

, 2017
openaire   +2 more sources

RETRACTION: CircPTPRM Accelerates Malignancy of Papillary Thyroid Cancer via miR-885-5p/DNMT3A Axis. [PDF]

J Clin Lab Anal
europepmc   +1 more source