Results 151 to 160 of about 3,435 (267)

Nasal Septal Perforation: A Potential Pitfall in Cotton Testing for Suspected Empty Nose Syndrome-A Case Series and Staged Algorithm. [PDF]

Int Forum Allergy Rhinol
Hosokawa Y, Kawamoto T, Sawada M, Harano M, Sato M, Kobayashi R, Ikezono T.   +6 more
europepmc   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

From Offline to Inline Without Pain: A Practical Framework for Translating Offline MR Reconstructions to Inline Deployment Using the Gadgetron Platform. [PDF]

Magn Reson Med
Ning Z, Brackenier Y, McElroy S, Silva SN, Cordero-Grande L, Rot S, Canas LS, Thornley RE, Leitão D, Poccecai D, Cantell A, Kerosi R, Price AN, Cleary J, Tournier DJ, Hutter J, Bridgen P, Di Cio P, Cleri M, Granlund I, Billimoria L, Blunck Y, Malik S, Modat M, Ourselin S, Steves CJ, Hajnal JV.   +26 more
europepmc   +1 more source

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

Longitudinal Analysis of Amyloid PET and Brain MRI for Predicting Conversion from Mild Cognitive Impairment to Alzheimer's Disease: Findings from the ADNI Cohort. [PDF]

Tomography
Kim DH.
europepmc   +1 more source

Metabolic Flux Analysis Reveals Cell Line‐Specific Rewiring in CHO Cells Following TCA Cycle Intermediate Feeding for Bioprocess pH Control

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells are the leading host for recombinant therapeutic protein production in the biopharma industry. In this study, we investigated how feeding acidic forms of tricarboxylic acid (TCA) cycle intermediates—malic acid, succinic acid, and α‐ketoglutaric acid—affects cell culture performance and metabolism in two ...
Sarah A. Sacco, Kevin J. Ruiz‐Márquez, Rachel Moen, Irina Trenary, Xiaolin Zhang, Xiaowen Wang, Malik Padellan, Henry Lin, Jamey D. Young   +8 more
wiley   +1 more source

Power Converter Design for Pulsed Electric Field-Based Milk Processing: A Proof of Concept. [PDF]

Foods
Domínguez-Soberanes J, Ruiz-Martinez OF, Davalos Hernandez F.   +2 more
europepmc   +1 more source

High‐performance tetrahedral palladium nanocatalyst for microwave‐assisted organic synthesis

Bulletin of the Korean Chemical Society, EarlyView.
Tetrahedral palladium nanoparticles anchored on graphene sheets (T‐Pd/graphene) were synthesized through a solvent‐free process involving thermal decomposition in an environment rich in carbon monoxide at elevated temperatures and have high catalytic activity for organic chemistry reactions. Abstract Palladium is widely recognized for its effectiveness
Dicky Annas, Kyung Hee Oh, Muthuchamy Nallal, Hack‐Keun Lee, Shin Wook Kang, Kwonho Jang, Jun‐Hyun Kim, Hyun Sung Kim, Ji Chan Park, Kang Hyun Park   +9 more
wiley   +1 more source

The coupling of global brain activity and cerebrospinal fluid flow as a potential predictive marker of brain amyloid-β accumulation. [PDF]

J Prev Alzheimers Dis
Tanaka Y, Kamagata K, Saito Y, Takabayashi K, Iseki R, Uchida W, Andica C, Hagiwara A, Wada A, Akashi T, Abe O, Aoki S, Alzheimer’s Disease Neuroimaging Initiative.   +12 more
europepmc   +1 more source

BODIPY‐based J‐aggregates: From supramolecular chemistry to NIR bioimaging and phototherapies

Bulletin of the Korean Chemical Society, EarlyView.
BODIPY dyes form ordered J‐aggregates through controlled supramolecular self‐assembly, producing narrow, red‐shifted absorption bands with small Stokes shifts. This review highlights design strategies governing J‐aggregation, structure–property relationships, and applications in sensing, bioimaging, and phototherapy, guiding functional BODIPY‐based ...
Pooja Sharma, Yeonkyeong Lee, Youngmi Kim   +2 more
wiley   +1 more source