Results 151 to 160 of about 18,778,543 (263)

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

open access: yesAdvanced Science, Volume 13, Issue 62, 9 November 2026.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang   +14 more
wiley   +1 more source

An LLC Resonant Converter with Double Resonant-Tanks for Wide-Input-Voltage-Range Applications

open access: yes, 2019
To achieve a wide input voltage range, an LLC resonant converter with double resonant-tanks is proposed. The topology can be conceived as two half-bridge circuits connected in series.
, Ezekiel Bokolonga
core  

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao   +5 more
wiley   +1 more source

Validation of plasma biomarker immunoassay‐based models for predicting brain amyloid positivity in cognitively impaired individuals

open access: yesAlzheimer's &Dementia, Volume 22, Issue 11, November 2026.
Abstract INTRODUCTION Combining Alzheimer's disease blood biomarkers may improve prediction of amyloid positivity (A+) compared with single biomarkers. METHODS Logistic regression models using plasma phosphorylated tau 217 (p‐tau217), amyloid beta (Aβ) 42, and Aβ40 were developed in cognitively impaired (CI) participants from Mayo Clinic Rochester (MCR)
Jeremy A. Syrjanen   +15 more
wiley   +1 more source

Brief Access Delay and Interruption to Reduce Social Media Use: Is it Effective?

open access: yesBehavioral Interventions, Volume 41, Issue 4, November 2026.
ABSTRACT Social media use is widespread among young adults, with many individuals frequently engaging with platforms that provide immediate access to entertainment, social interaction, and personalized content. Social media detoxification broadly refers to planned reductions, interruptions, or temporary restrictions in social media use.
Harley Ditzler   +3 more
wiley   +1 more source

Quinoxaline–Triazole Hybrids: Exploring the Impact of Substituent Architecture on Cytotoxic Potency and Receptor Interaction

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
A series of title compounds was synthesized, with 6e and 6k exhibiting the lowest IC50 values against MCF‐7, HeLa, and HepG2 cancer cell lines. Molecular docking and dynamics revealed strong binding to the adenosine A1 receptor (ΔG = –9.02 and –9.24 kcal/mol).
Bangar Reddy Vancha   +9 more
wiley   +1 more source

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