Results 41 to 50 of about 28,489 (221)

Distinct Microstructural Characteristic Lengths Defining Notch Fatigue Crack Initiation and Propagation, and Defect Tolerance in Advanced Steels

Advanced Engineering Materials, EarlyView.
Schematic representation of modes of microcrack nucleation, growth and temporary arrestment at different boundaries, with the criteria for crack propagation in three scenarios: (1) large notch, (2) defect/small sharp notch, and (3) long crack. This work revisits and integrates results on the fatigue behavior of advanced bainitic steels (in particular ...
Lucia Morales‐Rivas
wiley   +1 more source

Generation of binder-format-payload conjugate-matrices by antibody chain-exchange

Nature Communications
The generation of antibody-drug conjugates with optimal functionality depends on many parameters. These include binder epitope, antibody format, linker composition, conjugation site(s), drug-to-antibody ratio, and conjugation method.
Vedran Vasic, Steffen Dickopf, Nadine Spranger, Rose-Sophie Rosenberger, Michaela Fischer, Klaus Mayer, Vincent Larraillet, Jack A. Bates, Verena Maier, Tatjana Sela, Bianca Nussbaum, Harald Duerr, Stefan Dengl, Ulrich Brinkmann   +13 more
doaj   +1 more source

Predictive value of lymphocyte-to-monocyte ratio in the preoperative setting for progression of patients with breast cancer

BMC Cancer, 2018
Background The lymphocyte-to-monocyte ratio (LMR) has been used as a parameter reflecting systemic inflammation in several tumors, and is reportedly associated with prognosis in cancer patients. In this study, we evaluated the predictive value of LMR for
Wataru Goto, Shinichiro Kashiwagi, Yuka Asano, Koji Takada, Katsuyuki Takahashi, Takaharu Hatano, Tsutomu Takashima, Shuhei Tomita, Hisashi Motomura, Kosei Hirakawa, Masaichi Ohira   +10 more
doaj   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

Advanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang, Rachel P. White, Yashasvi Tharani, Michael A. Finocchiaro, Leona M. Ripple, Maksymilian Prondzynski, Tania Konry, Vassilios J. Bezzerides   +7 more
wiley   +1 more source

Association between lymphocyte-to-monocyte ratio and stroke-associated pneumonia: a retrospective cohort study [PDF]

PeerJ
Background Stroke-associated pneumonia (SAP) is a common complication of acute ischemic stroke (AIS) and is associated with increased mortality and prolonged hospital stays.
Xiaoqiang Li, Xiangmao Zhou, Hui Wang, Baifu Ruan, Zhibin Song, Guifeng Zhang   +5 more
doaj   +2 more sources

Prognostic value of platelet count and lymphocyte to monocyte ratio combination in stage IV non-small cell lung cancer with malignant pleural effusion. [PDF]

PLoS ONE, 2018
INTRODUCTION:A combination of platelet and lymphocyte to monocyte ratio (LMR) (abbreviated as COP-LMR) has been recently evaluated as systemic inflammatory marker for prognostication in lung cancer.
Jeong Uk Lim, Chang Dong Yeo, Hye Seon Kang, Chan Kwon Park, Ju Sang Kim, Jin Woo Kim, Seung Joon Kim, Sang Haak Lee   +7 more
doaj   +1 more source

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Advanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang, Yike Wang, Matthew R. Lowerison, Yue Xu, Murong Yi, Bing‐Ze Lin, YiRang Shin, Nathiya Vaithiyalingam Chandra Sekaran, Daniel A. Llano, Pengfei Song   +9 more
wiley   +1 more source

The Value of Systemic Inflammation Indices in Predicting Survival in Critical Flame Burn Patients: A Single-Center Retrospective Analysis

Hamidiye Medical Journal
Background: Burns are an important health problem that causes serious morbidity and mortality all over the world. Mortality in patients with critical burns is related to factors such as age, inhalation injury, and total burn surface area (TBSA).
Feyyaz Güngör, Hüseyin Kılavuz, Oğuzhan Aytepe, Mehmet Kuluş, Ceren Gökduman, Mustafa Turan   +5 more
doaj   +1 more source

Cellular immune inflammation markers in the blood of patients with gliomas of different malignancy grades

Сибирский онкологический журнал
Inflammatory blood markers are vital for immune responses and predicting cancer outcomes. Their roles in brain gliomas remain unclear. the aim of this study is to evaluate the diagnostic significance of these markers in patients with gliomas, taking into
S. S. Sklyar, A. S. Nechaeva, A. Yu. Ulitin, M. V. Matsko, V. E. Olyushin, K. A. Samochernykh   +5 more
doaj   +1 more source

Firearm carrying practices and motivations: A mixed methods study among adults and youth

American Journal of Community Psychology, EarlyView.
Abstract The purpose of this participatory action, mixed methods research study was to identify motivations related to firearm carrying from a qualitative perspective, and then to use quantitative research to characterize the patterns of motivations around carrying.
Krista R. Mehari, Colleen S. Walsh, L. Taylor Stevens, Jasmine N. Coleman, Alice Ellyson, Phillip N. Smith   +5 more
wiley   +1 more source