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A Peptide Encoded by a Putative lncRNA HOXB-AS3 Suppresses Colon Cancer Growth
Molecular Cell, 2017De Chen, Hongyang Huang, Min Hu
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Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy.
Journal of Controlled Release, 2022Exosomes as nanosized membrane vesicles, could targeted deliver therapeutic agents by modification with target ligands. Exosome-derived non-coding RNAs play a vital role in the development of tumors.
Xin Huang +8 more
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Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy.
Pharmacological Research, 2022Initiation and development of cancer depend on multiple factors that mutations in genes and epigenetic level can be considered as important drivers. Epigenetic factors include a large family of members and understanding their function in cancer has been ...
M. Hashemi +12 more
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LncRNA PVT1 regulates ferroptosis through miR-214-mediated TFR1 and p53.
Life Science, 2020AIM The study aims to investigate the roles of LncRNA and miRNA in ferroptosis in brain ischemia/reperfusion (I/R) in vivo and in vitro. MATERIALS AND METHODS qPCR assay was used to analyze lncRNA PVT1 and miR-214 expressions in acute ischemic stroke ...
Jing-jing Lu, Feng Xu, Hong Lu
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lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions.
Seminars in Cancer Biology, 2020Epithelial to mesenchymal transition (EMT) is a cellular process in which cells composing epithelial tissue lose requirements for physical contact with neighboring cells and acquire mesenchymal characteristics consisting of increased migratory and ...
Evan M. McCabe, T. Rasmussen
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Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics
Nature reviews. Molecular cell biology, 2022Takayuki Nojima, N. Proudfoot
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Revealing lncRNA Structures and Interactions by Sequencing-Based Approaches.
TIBS -Trends in Biochemical Sciences. Regular ed, 2019Long noncoding RNAs (lncRNAs) have emerged as significant players in almost every level of gene function and regulation. Thus, characterizing the structures and interactions of lncRNAs is essential for understanding their mechanistic roles in cells ...
X. Qian +4 more
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Using Network Distance Analysis to Predict lncRNA–miRNA Interactions
Interdisciplinary Sciences Computational Life Sciences, 2021Li Zhang +4 more
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