Results 351 to 360 of about 215,538 (386)

MALMPS: A Machine Learning‐Based Metabolic Gene Prognostic Signature for Stratifying Clinical Outcomes and Molecular Heterogeneity in Stage II/III Colorectal Cancer

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Chen et al. identified a metabolic gene prognostic signature with machine‐learning framework and assessed the prognostic value in independent CRC cohorts. The metabolic signature subtypes are characterized by specific metabolic and proteomic characteristics, and associated with distinct molecular pathway and therapeutic potential.
Hao Chen, Ze Wang, Chenglong Sun, Yang Zhong, Yuan Liu, Yikun Li, Tongchao Zhang, Yuan Zhang, Xingyu Zhu, Leping Li, Feifei Teng, Ming Lu, Wei Chong   +12 more
wiley   +1 more source

Uncovering essential lncRNAs through transcriptome-scale CRISPR-Cas13 screening. [PDF]

Adv Biotechnol (Singap)
Si J, Su X, Jin Z, Duan S.
europepmc   +1 more source

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

Advanced Science, Volume 12, Issue 37, October 6, 2025.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu, Rongxi Shen, Li Zhang, Xuejin Gao, Xinbo Wang, Changhua Zhang, Xi Chen, Xinying Wang   +7 more
wiley   +1 more source

Association between lncRNA H19 and osteoporosis in postmenopausal patients with type 2 diabetes mellitus. [PDF]

J Orthop Surg Res
Yang T, Feng X, Wang N, Zhang T, Zheng Z, Wang G.   +5 more
europepmc   +1 more source

Genetics of Response to ECT, TMS, Ketamine and Esketamine

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 7, Page 88-102, October 2025.
ABSTRACT Treatment‐resistant mood disorders are often managed with intensive interventions that include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ketamine, and esketamine, but the role of genetics in clinical response to those interventions is yet to be clearly determined.
Clio E. Franklin, Murat Altinay, Kala Bailey, Mahendra T. Bhati, Brent R. Carr, Susan K. Conroy, Khurshid Khurshid, William M. McDonald, Brian J. Mickey, James W. Murrough, Sean M. Nestor, Thomas Nickl‐Jockschat, Irving M. Reti, Gerard Sanacora, Nicholas T. Trapp, Biju Viswanath, Jesse H. Wright, Peter P. Zandi, James B. Potash   +18 more
wiley   +1 more source

Comprehensive Characterization of Long Non-Coding RNAs in Porcine Tissues: Expression Patterns and Functional Insights During Oocyte Development. [PDF]

Cells
Jiang Y, Li Y, Shen Q, Yuan X, Gao F, Ma B.   +5 more
europepmc   +1 more source

Interactions between LncRNAs and MAPK signaling pathways in the pathogenesis of breast cancer. [PDF]

Cancer Cell Int
Ding B, Wang X, Zhang Z, Wang Y, Bo W, Zhang M, Tian Z, Wang Y, Xue X, Zhang M.   +9 more
europepmc   +1 more source

SNHG16 promotes breast cancer progression by regulating the hsa-let-7b-5p/AURKA axis. [PDF]

Biochem Biophys Rep
Qiao Z, Tang Y, Li S, Lao Q, Xing Y, Zhang Q, Pan S, Bei C, Pang W, Liu H.   +9 more
europepmc   +1 more source

Crosstalk between hypoxia-inducible factor (HIF) and lncRNAs in digestive tumors: from molecular mechanisms to clinical translation. [PDF]

Front Cell Dev Biol
Gan L, Luo P, Zou J, Li W, Chen Q, Cheng L, Zhang F, Zhong H, Lu Y, Zheng L, Qian B.   +10 more
europepmc   +1 more source

Unveiling the oncogenic functions of lncRNA PSMG3-AS1: a review of its biological roles in cancer. [PDF]

Discov Oncol
Zhang H, Wang X.
europepmc   +1 more source