Results 111 to 120 of about 181,070 (306)

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro   +6 more
wiley   +1 more source

Effect of soil-pile contact parameters on pile bearing capacity value [PDF]

open access: yesE3S Web of Conferences
The soil and foundation elements are fundamental to the behavior of a structure. When the foundation soil has a low capacity, it is necessary to transmit the loads to a deeper and more resistant layer, using deep foundations.
Campos Darym   +5 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Heave induced reduction of friction capacity of pile embedded in clays

open access: yesMATEC Web of Conferences, 2017
Installation of new piles may cause heave which influence friction capacity of existing piles. The heave can be observed from the difference in the elevation of existing pile heads recorded before and after the installation of new piles or through load ...
Setyo Budi Gogot, Wibowo Tantri Gondo
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Seismic capacity of building constructed in slip formed load bearing wall panels

open access: yes, 2011
Constructing buildings using slip formed load bearing wall panels is becoming increasingly popular in Sri Lanka due to several advantages; low cost, environmental friendliness and rapid construction technique.
Moragaspitiya, Praveen, Susantha, K.A.S.
core  

CARRYING CAPACITY ANALYSIS OF CROSSED CYLINDRICAL ROLLER SLEWING BEARING UNDER COMBINED LOADS

open access: yesJixie qiangdu, 2016
The mechanics model of crossed cylindrical roller slewing bearing under combined radial,axial and tilting moment loads was established,this model considers the clearance parameter of the slewing bearing.
LI YunFeng, JIANG Di, CHENG YaBing
doaj  

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

open access: yesArthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier   +12 more
wiley   +1 more source

Instrumentation and Axial Load Testing of Displacement Piles

open access: yes, 2013
Despite the fact that results of many instrumented pile load tests have been reported in the literature, it is difficult to find well-documented instrumentation procedures that can be used when planning a load testing programme.
Salgado, Rodrigo   +4 more
core  

Performance of Round-Ended Concrete-Filled Steel Tubular Columns Under Combined Compression–Bending–Shear Loading

open access: yesBuildings
This study develops and validates a finite element model for round-ended concrete-filled steel tubular (CFST) columns subjected to combined compression–bending–shear loading using ABAQUS.
Yan Peng   +4 more
doaj   +1 more source

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