Results 211 to 220 of about 1,670,871 (318)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Chronic blood-borne viral hepatitis in a tertiary hospital in Al-Baha, Saudi Arabia: epidemiology, liver enzyme correlations, and treatment outcomes. [PDF]

BMC Infect Dis
Sallam TA, El-Badry RM, Alkully TH, Alfahemi HH, Halwani MA, Alzahrani KI, Alghamdi MA.   +6 more
europepmc   +1 more source

Simulation of Performance Formation Process of Loader with Wedge-like Working Elements as Part of Blast and Bulk Tunneling Complex

, 2017
G.S. Khazanovich, E. Yu. Voronova, A.V. Otrokov   +2 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

New design of plate implant for bone healing assessment using frequency measurement: a biomechanical cadaveric study. [PDF]

Sci Rep
Amarase C, Tangpornprasert P, Virulsri C, Chancharoen P, Tantavisut S.   +4 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Predictors of longitudinal viral load suppression among adults receiving first line antiretroviral therapy in Central Ethiopia. [PDF]

Sci Rep
Suwanbamrung C, Abraham A, Asheber M, Jaldo MM, Yakob T.   +4 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Intra and inter variation in training load, recovery state and technical-tactical performance across a standard microcycle in Sub-elite youth football players. [PDF]

Front Sports Act Living
Afonso P, Forte P, Branquinho L, Ferraz R, Garrido ND, Eduardo Teixeira J.   +5 more
europepmc   +1 more source

Pore Pressure Response of Undrained Two-Way Cyclic Loading of Silt

, 2018
Aminaton Marto
openalex   +2 more sources