Results 221 to 230 of about 4,586,899 (338)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Improved COT control strategy for CRM Boost-PFC circuits applied to marine integrated power systems. [PDF]

Sci Rep
Chen H, Xiao J, Lin J, Liu C, Zhuang S, Wang Z.   +5 more
europepmc   +1 more source

On the Effect of a Diastolic Load on the Diastolic Expansion of the Frog's Heart [PDF]

, 1896
F. W. Tunnicliffe
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Sensitivity of diffusion tensor imaging to regional mixed cerebrovascular pathology. [PDF]

Brain Commun
Ferris JK, Dahlby J, Rinat S, Greeley B, Ramirez J, Black SE, Boyd LA.   +6 more
europepmc   +1 more source

202) Data concerning Architectural Load (Part 2) : Snow Load(Civil Engineering)

, 1956
Kiyoo Matsushita, Masanori Izumi
openalex   +2 more sources

Lightening the Stevedore's Load, Unscientific Lawmaking, and more [PDF]

, 1920
C. W. Geiger
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Use the rating of perceived exertion to evaluate load in collegiate male soccer player, validity and influencing factors. [PDF]

Sci Rep
Li Z, Qin S, Li X, Ren D.
europepmc   +1 more source

Perils of the Deck-load [PDF]

, 1912
James G. McCurdy
openalex   +1 more source