Results 111 to 120 of about 1,598,056 (300)
L2/L3 equipment deployment scheme in PTN network architecture
Dianxin kexue, 2017 Relying on technological superiority,packet transport network（PTN）technology has become the main force in the construction of the transport network.In the early PTN network architecture,the L2/L3 equipment was deployed in the core layer.Therefore,it will
Xu DENG
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Forward Reliability Markets: Less Risk, Less Market Power, More Efficiency [PDF]
A forward reliability market is presented. The market coordinates new entry through the forward procurement of reliability options—physical capacity bundled with a financial option to supply energy above a strike price.
Peter Cramton, Steven Stoft
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Access by Capacity and Peak-Load Pricing [PDF]
Several European telecommunications regulatory agencies have recently introduced a fixed capacity charge (flat rate) to regulate access to the incumbents network.
Joan Calzada Aymerich
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Soil shear strength as a function of NSPT via Van der Veen extrapolation
REM: International Engineering JournalIn this study, a ground anchored wall located in Belo Horizonte containing 295 anchorages in a sandy silt soil was analyzed. The load capacity of all the anchors was calculated by extrapolation of the receipt tests by the Van der Veen method through the ...
Luma Alvarenga Carvalho de Vasconcelos +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Innovative design of composite structures: Use of curvilinear fiber format to improve structural efficiency [PDF]
To increase the effectiveness and efficiency of fiber-reinforced materials, the use of fibers in a curvilinear rather than the traditional straightline format is explored.
Charette, R. F., Hyer, M. W.
core +1 more source