Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Use of the Lorenz curve and the Gini index for the evaluation of HIV viral load distribution in an Italian community. [PDF]
Arsuffi S +8 more
europepmc +1 more source
Evaluation of Load Distribution in a Mandibular Model with Four Implants Depending on the Number of Prosthetic Screws Used for OT-Bridge System: A Finite Element Analysis (FEA). [PDF]
Grande F +4 more
europepmc +1 more source
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Comparison of Load Distribution in Subperiosteal Implants and Mini Plates in Orthognathic Surgery. [PDF]
Kasapoglu MB, Az ZAA.
europepmc +1 more source
Impairment characteristics of static balance and plantar load distribution of patients undergoing tibial cortex transverse distraction for diabetic foot ulcers. [PDF]
Fan ZQ, Liu DW.
europepmc +1 more source
Individual Load Model Parameter Estimation in Distribution Systems Using Load Switching Events [PDF]
Farajollahi, Mohammad +2 more
core
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
In case effects of proximal fibular osteotomy and total knee arthroplasty on load distribution in the human knee: A comparative finite element study. [PDF]
Ari B, Canlidinç M, Yaşar N, Gedik MA.
europepmc +1 more source
Load Distribution on PET-G 3D Prints of Honeycomb Cellular Structures under Compression Load. [PDF]
Basurto-Vázquez O +3 more
europepmc +1 more source

