Results 131 to 140 of about 1,578,755 (350)

Intervertebral Disc‐on‐a‐ChipMF: A New Model for Mouse Disc Culture via Integrating Mechanical Loading and Dynamic Media Flow (Adv. Mater. Technol. 21/2023) [PDF]

open access: bronze, 2023
Wanqing Xie   +14 more
openalex   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Advanced thermal energy management: A thermal test bed and heat pipe simulation [PDF]

open access: yes
Work initiated on a common-module thermal test simulation was continued, and a second project on heat pipe simulation was begun. The test bed, constructed from surplus Skylab equipment, was modeled and solved for various thermal load and flow conditions.
Barile, Ronald G.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

A distributed robust state estimation method based on alternating direction method of multipliers for integrated electricity‐heat system

open access: yesIET Energy Systems Integration
Integrated electricity‐heat system (IEHS) has been paid more and more attention in recent years for its advantage in improving energy efficiency, reducing carbon emissions and increasing renewable energy penetration. To ensure the safety, reliability and
Yanbo Chen   +9 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Effects of surface loading on groundwater flow and skeletal deformation [PDF]

open access: bronze, 2019
YU Qing-yang   +6 more
openalex   +1 more source

Tidal Energy Round Robin Tests: A Comparison of Flow Measurements and Turbine Loading [PDF]

open access: gold, 2021
Rodrigo Martinez   +10 more
openalex   +1 more source

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