Results 231 to 240 of about 13,696,623 (302)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Load frequency control of multi-area power system incorporated renewable energy considering electrical vehicle effect using modified cascaded controller tuned by BESSO algorithm.

Heliyon
Ghafoor R, Guanghua L, Gulzar MM, Irfan R, Alqahtani M, Khalid M.   +5 more
europepmc   +1 more source

Bio-inspired functional recursion enables multi-mode locomotion in a 140-mg morphing microrobot. [PDF]

Microsyst Nanoeng
Wang Y, Wang Z, Wang Z, Wu Y, Lu S, Zhang W, Guan Y, Zhi P, Geng Z, Xu H, Zhang J, Fu Y.   +11 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Psychophysical estimates guidelines for maximal acceptable loads during unilateral overhead work while wearing an exoskeleton in construction workers. [PDF]

PLoS One
Herrera Valerio MC, Howard-Azzeh M, Yung M, Yazdani A.   +3 more
europepmc   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Vibration-induced dynamic structural superlubricity on MoS₂/Au(111) under ultrahigh vacuum. [PDF]

Beilstein J Nanotechnol
Huang S, Song Y, Hinaut A, Navarro-Marín G, Cammarata A, Meyer E, Glatzel T.   +6 more
europepmc   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Low-cost programmable sine wave driver for inductive loads with built-in current sensing. [PDF]

HardwareX
Labuda M, Wohlmuthova V, Janousek L.
europepmc   +1 more source

An operational spatiotemporal prediction framework for sector congestion in air traffic management. [PDF]

PLoS One
Chen H, Gao Z, Yan X, Yi Y, Gong J, Wu L.   +5 more
europepmc   +1 more source