Results 131 to 140 of about 129,952 (301)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Coordinated frequency modulation strategy considering source–load uncertainty

open access: yesFrontiers in Energy Research
IntroductionWind turbine generators (WTGs) and electric vehicles (EVs) are used as source-side and load-side resources, respectively. And the uncertainties of WTGs output and EVs charging load seriously affect the frequency stability of the power system.
Xiaohong Dong   +4 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Optimal control strategies for high-efficiency non-isolated DC-DC buck converters in IoT applications: A comparative study

open access: yesHeliyon
A DC-DC buck converter (DDBC) plays a crucial role in facilitating the rapid evolution of Internet of Things (IoT) applications across a broad spectrum of load requirements.
Sivakumar Kumaraguruparan   +1 more
doaj   +1 more source

Recent Developments in Active Load Modulation PA Architectures

open access: yes
IMS Workshop WMD: Recent Development in Wideband and Efficient Doherty PAs for 5G and 6G Wireless Communications 1. Recent Developments in Active Load Modulation PA Architectures     Authors: Han Zhou and Christian Fager 2.
Fager, Christian,, Zhou, Han,
core  

A Two-Port Nonlinear Dynamic Behavioral Model of RF PAs Subject to Wideband Load Modulation

open access: yes, 2018
This work presents a full two-port, i.e., double input-double output, behavioral modeling approach suitable for radio frequency power amplifiers (PAs) in the presence of dynamic load modulation (DLM).
Lukasik, Konstanty   +11 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Comparative Assessment of Modulation Strategies in Modular Multilevel Converters: An Attempt for a Better Compromise Between the Efficiency and Capacitor Voltages' Dispersion

open access: yesIEEE Open Journal of the Industrial Electronics Society
Modulation techniques for Modular Multilevel Converters (MMCs) encounter a limit in the tradeoff between reducing the total harmonic distortion (THD) of the load current and minimizing the number of commutations, primarily due to traditional sorting ...
Anthony Abdayem   +5 more
doaj   +1 more source

Improving contactless technology by increase of transponder load modulation with serial capacitor

open access: yes, 2020
-Proven chip technology based on International Standards can be used to implement person-related, secure contactless technology also into objects defining smaller antenna sizes than cards.
Martin Münzer   +2 more
core  

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