Results 91 to 100 of about 4,744,882 (298)
Applied SciencesThis study quantifies vertical earth pressure on the roofs of box culverts under high fills in valley terrain using centrifuge model tests with expanded polystyrene (EPS) geofoam for load mitigation.
Conglin Guo +5 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
How much load can my pallet carry?
, 2018 Properly determining the exact load carrying capacity of a pallet is essential to ensure the effectiveness of the supply chain. Multiple testing procedures are published by different organizations and all could be used to estimate the load capacity of ...
Horvath, Laszlo
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Performance assessment of a novel active mooring system for load reduction in marine energy converters [PDF]
, 2016 The full text of this paper is available via the ICOE Library link in this record.Mooring systems affect extreme and fatigue loading in moored wave and tidal stream energy converters driving reliability, device survival and energy extraction efficiency ...
Johanning, L +4 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Harm reduction among injecting drug users - evidence of effectiveness [PDF]
, 2010 This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Hutchinson, Sharon +5 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A comparative study of four rod load reduction techniques for deep-rod pumping
Journal of Petroleum Exploration and Production Technology, 2017 In deep-rod pumping wells, polished rod load tends to be very high and even exceeds the operating range of the pumping unit. To tackle the problem, mainly four rod load reduction techniques have been designed till now.
Yi Zuo, Xiaodong Wu
doaj +1 more source
Model Order Reduction for Systems with Moving Loads
at - Automatisierungstechnik, 2014 Abstract In this contribution we present two approaches allowing to find a reduced order approximant of a full order model featuring a moving load term. First, we apply the Balanced Truncation (BT) method to a switched linear system (SLS) using the special structure given in the spatially discretized model. The second approach treats the
Norman Lang, Jens Saak, Peter Benner
openaire +3 more sources