Results 71 to 80 of about 277,718 (342)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Multi-Time-Scale Hierarchical Optimization Scheduling Method for DC Power Transmission Systems Considering Source-Load Matching Deviation [PDF]

open access: yesDianli jianshe
[Objective] To enhance the economic efficiency of large-scale cross-regional and cross-provincial wind and solar power absorption,a multi-time-scale hierarchical optimization scheduling method for DC power transmission systems considering the source-load
WANG He, LI Zeren, YU Hua’nan, BIAN Jing, LI Shiqiang
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

An Optimal Trade-off between Content Freshness and Refresh Cost

open access: yes, 2010
Caching is an effective mechanism for reducing bandwidth usage and alleviating server load. However, the use of caching entails a compromise between content freshness and refresh cost.
Cho   +7 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Multi-User Optimal Load Scheduling of Different Objectives Combined with Multi-Criteria Decision Making for Smart Grid

open access: yesFuture Internet
Load balancing between required power demand and the available generation capacity is the main task of demand response for a smart grid. Matching between the objectives of users and utilities is the main gap that should be addressed in the demand ...
Yaarob Al-Nidawi   +3 more
doaj   +1 more source

Divisible Load Scheduling and Markov Chain Models

open access: yesComputers & Mathematics with Applications, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Moges, M.A., Robertazzi, T.G.
openaire   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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