Results 51 to 60 of about 823,198 (305)

Improved natural balancing with modified phase shifted PWM for single-leg five-level flying-capacitor converters [PDF]

open access: yes, 2012
Flying capacitor converters (FCCs), as most multilevel converter topologies, require a balancing mechanism of the capacitor voltages. FCCs have the valuable property of natural voltage balancing when a special modulation technique is used.
Melkebeek, Jan   +3 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Experimental investigation and analytical prediction on bond behaviour of CFRP-to-concrete interface with FRP anchors

open access: yesCase Studies in Construction Materials, 2023
Hybrid bonded technology with fiber-reinforced polymer (FRP) anchors can effectively improve the load capacity of carbon fiber-reinforced polymer (CFRP)-to-concrete interface. To investigate the reinforcement effect of FRP anchors, tensile shear tests of
Kun Dong   +4 more
doaj   +1 more source

Genetic markers associated with field PRRSV-induced abortion rates [PDF]

open access: yes, 2019
In gilts and sows, the more severe clinical manifestation of PRRSV occurs in late gestation and can result in up to 40% of abortion incidence. Despite the known genetic component in the resilience to PRRSV, there is scarce information regarding the ...
Blasco-Felip, María   +4 more
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Nonlinear bending analysis of trapezoidal panels under thermo-mechanical load

open access: yesForces in Mechanics, 2022
The nonlinear bending responses of trapezoidal panels under thermal load are investigated here using the higher order degenerated shell element. First-order shear deformation theory is used here and employed the finite element method with account of von ...
Emarti Kumari, Shiv Lal
doaj   +1 more source

Damage process of a fiber bundle with a strain gradient [PDF]

open access: yes, 2008
We study the damage process of fiber bundles in a wedge-shape geometry which ensures a constant strain gradient. To obtain the wedge geometry we consider the three-point bending of a bar, which is modelled as two rigid blocks glued together by a thin ...
Kun, Ferenc, Nagy, Sandor
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Abrasive Wear Performance of Jute–Glass–Carbon-Reinforced Composites: Effect of Stacking Sequence and Fibers Relative Amounts

open access: yesJournal of Natural Fibers, 2021
In the present study, water absorption and its subsequent effect on abrasive wear performance of jute–glass–carbon-reinforced composites have been investigated. Nine laminates were fabricated in inter–ply configuration with hand lay–up technique.
M. A. Abd El–Baky, M. Kamel
doaj   +1 more source

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