Results 191 to 200 of about 46,083 (304)

Textile Actuation Based on In‐Air Actuating Polypyrrole‐Based Tape Yarns for Wearable Soft Robotics: Toward On‐Body Applications

Advanced Robotics Research, EarlyView.
This work reports on the actuation behavior of CP‐based polypyrrole/PVdF TYs soaked in electrolyte/ionic liquids and woven actuators where such TYs are integrated. These studies are important toward the creation of on‐body applications such as wearable soft robotics, where textiles offer many advantages such as increased force, integrated electrical ...
Carin Backe, Jose G. Martinez, Li Guo, Edwin W. H. Jager, Nils‐Krister Persson   +4 more
wiley   +1 more source

A retrospective comparison of CMV DNA detection in reproductive tract secretions <i>versus</i> urine: increased yield with combined sample testing. [PDF]

PeerJ
Hu L, Bai Y, Wu P, Li S, Wu K, Zhu B, Binbin Y.   +6 more
europepmc   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Modeling viral shedding and symptom outcomes in oseltamivir-treated experimental influenza infection. [PDF]

PLoS One
Fujita Y, Akao M, Tatematsu D, Iwami S, Nakamura N, Iwanami S.   +5 more
europepmc   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Exploring the Relationship Between Comorbidities and Prolonged Viral Shedding in COVID-19: A Cycle Threshold Value-Based Investigation. [PDF]

Can J Infect Dis Med Microbiol
Wisaksana R, Philo P, Putri FI, Prayuda CB, Susandi E, Widyatmoko L, Alisjahbana B, Kulsum ID, Hartantri Y.   +8 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Cytomegalovirus DNAemia in Hospitalized Adults With SARS-CoV-2 Infection Requiring Supplemental Oxygen: Virologic and Clinical Characteristics and Association With Outcomes. [PDF]

J Infect Dis
Boeckh M, Xie H, Stevens-Ayers T, Sircy L, Zamora D, Goldman JD, Woods CW, Stapleton RD, Rubenfeld G, Kalil A, Jerome KR, Dasgupta S, Limaye AP.   +12 more
europepmc   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source

Development and Immune Efficacy Evaluation of Two Live Triple-Gene-Deleted Vaccine Candidates Against Bovine Herpesvirus Type 1. [PDF]

Animals (Basel)
Gu Y, Duan H, Ji C, Lin H, Lai Y, Zhang J, Zhang C, Huo S, Ni Z, Yun T, Ye W, Hua J, Chen L, Fu Y, Zhu Y, Pan Z.   +15 more
europepmc   +1 more source