Results 91 to 100 of about 1,619,191 (308)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Pemanfaatan Arsitektur Microservice untuk Peningkatan Performansi Website Lomba nasional Kreativitas Mahasiswa

open access: yesJurnal Teknologi Informasi dan Ilmu Komputer
Lomba Nasional Kreativitas Mahasiswa (LO Kreatif) merupakan ajang tahunan yang diadakan oleh APTISI 7 Jatim untuk mahasiswa perguruan tinggi swasta di Indonesia.
Sanjaya, Murnawan
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Full load shop testing of 18,000-hp gas turbine driven centrifugal compressor for offshore platform service: Evaluation of rotor dynamics performance [PDF]

open access: yes
The results for in-plant full load testing of a 13.4 MW (18000 HP) gas turbine driven centrifugal compressor are presented and compared to analytical predictions of compressor rotor stability.
Kirk, R. G., Simpson, M.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A TWO-DIMENSION TIME-DOMAIN-THRESHOLD METHOD FOR LOAD SPECTRA EDITING AND ITS APPLICATION

open access: yesJixie qiangdu, 2022
In order to avoid dependence of structural local detailed strain/stress spectrum of the traditional Time Correlated Fatigue Damage Editing method, a Spectra Two-dimension Time-domain-threshold Editing(STTE) method was proposed for the problem of spectrum
YU JiaWei   +3 more
doaj  

SHALLOW FLAT SOFFIT PRECAST CONCRETE FLOOR SYSTEM [PDF]

open access: yes, 2014
A precast concrete floor system that eliminates the need for column corbels and beam ledges while being very shallow. The main advantages of the present system include a span to-depth ratio of 30, a flat soffit, economy, consistency with prevailing ...
Morcous, George, Tadros, Maher
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Fracture Testing with Surface Crack Specimens [PDF]

open access: yes
Recommendations are given for the design, preparation, and static fracture testing of surface crack specimens. The recommendations are preceded by background information including discussions of stress intensity factors, crack opening displacements, and ...
Orange, T. W.
core   +1 more source

Microbial load monitor [PDF]

open access: yes
Attempts are made to provide a total design of a Microbial Load Monitor (MLM) system flight engineering model. Activities include assembly and testing of Sample Receiving and Card Loading Devices (SRCLDs), operator related software, and testing of ...
Caplin, R. S., Royer, E. R.
core   +4 more sources

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