Results 121 to 130 of about 3,483,119 (301)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Total and partial knee arthroplasty implants that maintain native load transfer in the tibia. [PDF]
Bone Joint Res, 2022 Munford MJ +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Journal of Materials and Engineering Structures, 2020 The paper presents the vertical bearing capacity of bored piles from the bi-directional load test (O-Cell method) at the Tra Khuc dam-bridge project in Quang Ngai province.
Dao Huu DO +3 more
doaj
Parametric Studies of the Load Transfer Platform Reinforcement Interaction with Columns. [PDF]
Materials (Basel), 2021 Gajewska B, Gajewski M, Lechowicz Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Plantar load transfer in children: a descriptive study with two pathological case studies. [PDF]
BMC Musculoskelet Disord, 2021 Brierty A +6 more
europepmc +1 more source
DEM modelling of shaft load transfer behavior of rock-socketed piles
The behavior of rock-socketed piles (RSPs) has been the aim of extensive research through field load tests, centrifuge tests, numerical simulations, etc.
Gutiérrez-Ch, J. G. +3 more
core +1 more source
, 2009 The aim of this study is to examine numerically the effects of spark timing and load parameters on the in-cylinder heat transfer of a SI engine by using experimental engine test data.
SAYIN, CENK
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source