Results 201 to 210 of about 1,653,673 (316)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A parametric study of mechanoporation through microfluidic design to modulate shear, compressive, and adhesion forces and loading rates.

Lab Chip
Gupta A, Van Zyl J, Bushey C, Shankles P, Amiri HA, Pratx G, Alexeev A, Sulchek T.   +7 more
europepmc   +1 more source

Robust Adaptive Beamforming Algorithm Based on Improved Generalized Linear Combination. [PDF]

Sensors (Basel)
Gao Z, Zuo R, Huang P, Xu W, Tan W, Wu Z.   +5 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Lifetime Physical Loading and Magnetic Resonance-Derived Intervertebral Disc Health in Adults With Chronic Low Back Pain: A Cross-Sectional Study. [PDF]

JOR Spine
Samanna CL, Neason C, Tagliaferri SD, Mitchell UH, Caldwell M, Imran A, Nez HR, Belavý DL, Miller CT, Scott D, Mundell NL, Buntine P, Owen PJ.   +12 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Encapsulation of Menthol in Bimodal Mesoporous Silica via Normal-Temperature and Alcohol-Thermal Loading Methods for Achieving Sustained Releasing Performances. [PDF]

Nanomaterials (Basel)
Bi Y, Ma T, Wang A, Liu F, Xu R, Munir T, Sun J, Fu W, Xu D.   +8 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

The Impact of Football Boot Design on Lower Limb Injury Risk: A Systematic Review. [PDF]

Sports Med Open
Yang F, Huang J, Wei Q, Jiang L, Liang D.   +4 more
europepmc   +1 more source