Results 201 to 210 of about 929,374 (358)

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

open access: yesAdvanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen   +16 more
wiley   +1 more source

Stichwort: Formate der Hochschulweiterbildung

open access: yesZeitschrift Hochschule und Weiterbildung, 2019
Wolfgang Jütte, Claudia Lobe
doaj   +1 more source

Pulmonary azygous lobe [PDF]

open access: yesQJM: An International Journal of Medicine, 2017
F, Lin, Y, Xu, L, Liu
openaire   +2 more sources

Diffusion‐MRI‐Based Estimation of Cortical Architecture via Machine Learning (DECAM) in Primate Brains

open access: yesAdvanced Science, EarlyView.
We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu   +7 more
wiley   +1 more source

Parallel encoding of speech in human frontal and temporal lobes. [PDF]

open access: yesNat Commun
Hullett PW   +4 more
europepmc   +1 more source

A Case of Pilocytic Astrocytoma with BRAF V600E Mutation and Anaplastic Features occurred in Adult Temporal Lobe

open access: diamond, 2017
Yuki Kozaki   +7 more
openalex   +2 more sources

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

open access: yesAdvanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu   +10 more
wiley   +1 more source

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