NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex
Advanced Science, EarlyView.The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang +8 more
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Pulmonary endarterectomy and lung resection achieving therapeutic success in rarely encountered large cavitary infarctions following pulmonary embolism: a case report. [PDF]
J Cardiothorac SurgBakr L +3 more
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XIII. Cerebral Abscesses of the Frontal Lobe Originating from the Frontal Sinus and other Intracranial Complications Resulting from Inflammatory Processes of the Nasal Accessory Sinuses [PDF]
, 1919 Frithjof Leegaard
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Advanced Science, EarlyView.This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li +8 more
wiley +1 more source
Minimally invasive autopsy as a useful tool for RNA extraction in molecular pathology of lung diseases. [PDF]
Braz J Med Biol ResBatah SS, Fabro AT.
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EPILEPTIC ATTACKS PRECEDED BY SUBJECTIVE AUDITORY AND TASTE SENSATIONS, PROBABLY DUE TO A TUMOUR OF THE LEFT TEMPORO-SPHENOIDAL LOBE. [PDF]
, 1900 Jeffrey M. Clarke
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Advanced Science, EarlyView.CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee +13 more
wiley +1 more source
Peritumoral MRI findings and brain herniations in epileptic dogs with prosencephalic brain tumors: a multicentre retrospective study. [PDF]
Front Vet SciTabbì M +9 more
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An account of a small lobe of the human prostate gland, which has not before been taken notice of by anatomists [PDF]
Everard Home
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ON THE PRESSOR ACTIVITY AND STABILITY OF DIFFERENT MIXTURES OF EPHEDRINE AND PITUITARY (POSTERIOR LOBE) EXTRACT [PDF]
, 1946 K. I. Melville
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