Results 61 to 70 of about 83,367 (302)

Invasive lobular carcinoma with extracellular mucin as a distinct variant of lobular carcinoma: a case report

Diagnostic Pathology, 2012
The differences between invasive lobular and ductal carcinomas affect the diagnostic and therapeutic management for patients with breast cancer. In most cases, this can be accomplished because of distinct histomorphologic features. However, occasionally,
Haltas Hacer, Bayrak Reyhan, Yenidunya Sibel, Kosehan Dilek, Sen Meral, Akin Kayihan   +5 more
doaj   +1 more source

Molecular drivers of lobular carcinoma in situ [PDF]

, 2015
Lobular carcinoma in situ (LCIS) is considered to be a risk factor for the development of invasive breast carcinoma, but it may also be a non-obligate precursor to invasive lobular carcinoma (ILC).
Peter C. Lucas, Daniel D. Brown, Lucas, PC, Clark, Beth Z., McAuliffe, Priscilla F., Greg GregJ. Logan, Rachel C. Jankowitz, Beth Z. Clark, Priscilla F. McAuliffe, Oesterreich, S, Steffi Oesterreich, McAuliffe, PF, Brown, Daniel D., Oesterreich, Steffi, Lucas, Peter C., Jankowitz, RC, Logan, Greg J., Logan, GJ, Jankowitz, Rachel C., Dabbs, DJ, Dabbs, David J., Clark, BZ, Brown, DD, David J. Dabbs   +23 more
core   +1 more source

MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi‐Scale Information and Metric Learning Framework for scDNAm Data

Advanced Science, EarlyView.
MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia, Siyu Li, Songming Tang, Keju Gu, Shengquan Chen   +4 more
wiley   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

Lobular breast carcinoma metastatic to the endometrium in a patient under tamoxifen therapy: A case report

SAGE Open Medical Case Reports, 2020
Metastatic carcinomas to the uterus are rare and usually originate from nearby gynecologic sites, most commonly from the ovaries. Among non-gynecologic origins, breast tumors are the most frequent primaries, predominantly the lobular carcinoma type. A 69-
Mariangela Gomez, Kerry Whitting, Rana Naous   +2 more
doaj   +1 more source

Micro/Nanoscale Acoustic Manipulation: From Particle Control to Autonomous Microswimmers

Advanced Science, EarlyView.
This conceptual framework illustrates acoustic technology as a multifunctional platform enabling passive particle manipulation across scales and autonomous propulsion of microswimmers. ABSTRACT Acoustic manipulation and propulsion technologies have emerged as powerful platforms for micro/nanoscale control, enabled by their non‐contact operation, label ...
Jiahui Chu, Lemin Zhang, Xu Wang, Wenzong Li, Yahua Liu   +4 more
wiley   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Gastric metastasis of triple negative invasive lobular carcinoma

Rare Tumors, 2015
Invasive lobular carcinomas are the second most common type (5% to 15%) of invasive breast carcinomas. The most frequent sites of breast cancer metastasis are the local and distant lymph nodes, brain, lung, liver, and bones; metastasis to the ...
Caglayan Geredeli, Osman Dogru, Ethem Omeroglu, Farise Yilmaz, Faruk Cicekci   +4 more
doaj   +1 more source

Hepatic lobular inflammation scores.

, 2014
Data presented as the n (percentage) of mice from each group having an inflammation score of 0, 1, 2, or 3. The percentages may not equal 100% due to rounding.aP-value for the ordinal logistic regression analysis evaluating the impact of genotype (Ephx2−/
Kenneth B. Tomer (589458), Kimberly C. Vendrov (643558), H. Michael Jones (643561), Tricia M. Miller (643559), Craig R. Lee (400783), Artiom Gruzdev (643557), Liza Makowski (159623), Darryl C. Zeldin (16449), Robert N. Schuck (643556), Zhenghong Xu (412193), Fred B. Lih (643560), Samuel M. Poloyac (643563), Leaf Huang (643562), Matthew L. Edin (200313), Weibin Zha (240201), Laura M. DeGraff (386681)   +15 more
core   +1 more source

Developmental Environmental Chronotoxicity by Polystyrene Nanoplastics Exacerbates High‐Fat Diet‐Induced Pediatric MAFLD Through Circadian Disruption and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Polystyrene nanoplastics exacerbate high‐fat diet‐induced metabolic dysfunction in an age‐dependent manner. Juvenile mice exhibit greater susceptibility, characterized by circadian disruption, impaired mitochondrial function, reduced energy metabolism, and enhanced hepatic lipid accumulation.
Peihao Xu, Shuting Huang, Leilei Zhu, Junyi Huang, Kewei Li, Guangming Li, Jiannong Wu, Mingyuan Zhou, Fangmei Zhou, Zhishan Ding, Yingzhi Shen   +10 more
wiley   +1 more source