Results 31 to 40 of about 6,999,919 (275)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
PulmonologyBackground This study estimated the risk of exacerbations, cardiovascular (CV) death and all-cause death in COPD patients, according to their exacerbation profile.Methods A real-world, retrospective study, based on electronic health records from the ...
Paula Simão +13 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Citizen Participation in the Digital Era: A Comparative Perspective between Thailand and South Korea
Policy & Governance ReviewCitizen participation is a vital component of public administration in the 21st century. This study compares Thailand and South Korea to examine how digital governance frameworks influence civic engagement, focusing on policy design, administrative ...
Pornnatcha Wongsa, Grichawat Lowatcharin
doaj +1 more source
District Offices on Peasants’ Affairs in Belarus (1878-1901)
Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2017 An institute of conciliators was established for realization of agrarian reform of 1861. However, during the 1960s it satisfied the government less and less as it was not legally subordinate to the local government.
Svetlana A. Tolmacheva
doaj +1 more source
Council on Academic Affairs: Minutes (November 28, 2012) [PDF]
, 2011 Minutes from the Council on Academic Affairs' meeting on November 28 ...
University of Nebraska at Kearney Academic Affairs Committee +1 more
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Bottom-up cultural initiatives in local communities – between retreat and social engagement
AS: Andragoška Spoznanja, 2018 The goal of this text is to discuss the ways in which the creators/organizers of bottom-up cultural initiatives in local communities shape relationships with these communities and to present their involvement in the communities’ affairs and problems ...
Sylwia Słowińska
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Council on Academic Affairs: Minutes (November 15, 2023)
, 2023 Minutes from the Council on Academic Affairs' meeting on November 15 ...
Ohio State University. Council on Academic Affairs
core +1 more source