Results 141 to 150 of about 1,104,476 (332)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Law and Institutions: two reasons for Sicilian backwardness? [PDF]

open access: yes
Many reasons for the low level of local development in Sicily have been advanced through the years, often connected to historical and geographical explanations. More frequently the reasons of the backwardness (better low rate of development) is connected
Consoli, Andrea, Spagano, Salvatore
core   +1 more source

Governance Structures for Local Economic Development in Croatia [PDF]

open access: yes, 2005
Who should take care of local economic development in Croatia? This question seems trivial, however, there are still some open questions. According to current legislation, local economic development is an administrative task of the 21 counties, the ...
Rasic-Bakaric, Ivana   +2 more
core  

Nanozymes Integrated Biochips Toward Smart Detection System

open access: yesAdvanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen   +10 more
wiley   +1 more source

Problems and prospects of local self-government reformation in Ukraine [PDF]

open access: yes
Аналізується чинне українське законодавство з питань місцевого самоврядування, визначено його недоліки та надано пропозиції щодо реформування місцевого самоврядування в Україні на основі європейського досвіду.The article analyzes the current Ukrainian ...
Myshchak, Ivan M.   +1 more
core   +1 more source

The functional measuring of the credit financing of grant of public benefits is on local and regional levels [PDF]

open access: yes, 2016
Стаття присвячена виявленню можливостей збільшення доходів регіональних та місцевих бюджетів шляхом здійснення запозичень. В публікації розглядаються позитивні та негативні наслідки здійснення запозичень органами місцевого та регіонального самоврядування.
Volokhova, I.   +2 more
core  

Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring

open access: yesAdvanced Science, EarlyView.
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley   +1 more source

Reforming regional government system and social well-being of local population: territorial aspects

open access: yesВестник Северо-Кавказского федерального университета
Introduction. The relevance of the topic is justified by the need to summarize the interim results of the pilot project on the formation of a single-level system of local self-government and its impact on the socio-economic development of territories in ...
S. N. Kalyugina
doaj   +1 more source

Models financing regional development of Eastern Croatia [PDF]

open access: yes
The paper discusses the reasons for the low development level of Eastern Croatia, as well as possible ways of overcoming this situation. The revenues of local and regional self-government are frequently insufficient to finance development projects ...
Matić, Branko, Serdarušić, Hrvoje
core   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

open access: yesAdvanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang   +5 more
wiley   +1 more source

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