Results 291 to 300 of about 5,302,191 (386)

Local Anesthesia

, 2018
openaire   +3 more sources

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source

Effect of precooling on the assessment of pain during local anesthesia in adults: A systematic review and meta-analysis. [PDF]

J Clin Exp Dent
de Andrade ABL, de Moraes SLD, de França AJB, Costa RTF, Pellizzer EP, Vasconcelos BCDE.   +5 more
europepmc   +1 more source

Bionic Microneedle Patch Inspired by Drosophila Tarsal Paws Boosts Healing in Bacterial Infectious Stomatitis

Advanced Science, EarlyView.
Microneedle suction cup patches, prepared using bionic Drosophila tarsal claws, can effectively treat bacterial infectious stomatitis by rapidly and efficiently leveraging multiple effects, including antibacterial and anti‐inflammatory properties, promotion of vasodilation, and active mechanical contraction of the wound.
Jiaqi Qin, Cewen Hu, Xiaohong Ran, Huajing Zeng, Jie Zhang, Bin Liu, Zengjie Fan   +6 more
wiley   +1 more source

Case report: Local anesthesia with lidocaine infiltration for extended-release buprenorphine therapy. [PDF]

Front Psychiatry
Azar P, Kim JJ, Rohani E, Newman-Azar D, Narimani M, Machado J, Li VW.   +6 more
europepmc   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Pre-injection local anesthesia does not affect experienced pain in intra-articular hip injections. [PDF]

World J Orthop
Albagli A, Rath E, Druckmann I, Efrima B, Kazum E, Parnes N, Sandler AB, Tyler J, Amar E.   +8 more
europepmc   +1 more source

Gradient Solvent Replacement‐Mediated Formation of High‐Strength Hydrogel‐Forming Microneedle for Long‐Term Drug Delivery

Advanced Science, EarlyView.
A high‐strength pH‐responsive hydrogel‐forming microneedle integrates gradient solvent replacement to enhance the mechanical properties of the acrylonitrile‐acrylic acid copolymer network, ensuring robust transdermal penetration and long‐term drug release.
Hui Li, Fengzhen Meng, Chengwei Hu, Zhiyun Wu, Liuzhi Hao, Caijun Sun, Lijing Fang, Fan Pan, Shaoquan Bian, Huipeng Li, Mingjun Li, Bo Liu, Xiaoli Zhao   +12 more
wiley   +1 more source

Correction for Epstein-Barash et al., Prolonged duration local anesthesia with minimal toxicity. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Endoscopic Hematoma Evacuation Under Local Anesthesia for Acute Intracerebral Hemorrhage in Older Patients: A Case Series. [PDF]

Cureus
Tsuchiya T, Koike T, Takenobu A, Morita A, Teraoka A.   +4 more
europepmc   +1 more source