Results 111 to 120 of about 6,228,010 (302)

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Can repeated exposure to morphine change the spinal analgesic effects of lidocaine in rats?

Journal of Research in Medical Sciences, 2011
Background: Chronic opium exposure leads to altered response to opioid compounds. The aim of this study was to assess the behavioral effects of opium tolerance on the analgesic effects of intrathecal lidocaine in rats.
Ali Dabbagh, Shervin Farkhondehkish Moghadam, Samira Rajaei, Zahra Mansouri, Homa Shardi Manaheji   +4 more
doaj  

Effect of a Local Anesthetic Injection Kit on Pain Relief and Postoperative Recovery After Transumbilical Single-Incision Laparoscopic Cholecystectomy

, 2023
Na Yang,1,* Qing-Yu Tao,1,* Jing-Yi Niu,1 Hao Sun,1 Yan He,1,2 Yong-Bo Hou,1,2 Hong Luo,1 Zhi Zhang,3 Jun-Ma Yu1 1Department of Anesthesiology, the Third Affiliated Hospital of Anhui Medical University (The First People’s Hospital of Hefei ...
Niu JY, He Y, Hou YB, Zhang Z, Yang N, Tao QY, Luo H, Sun H, Yu JM   +8 more
core  

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

handley-lab/anesthetic: v2.7.1

<h2>What's Changed</h2> <ul> <li>Update actions for Node.js 16 deprecation by @AdamOrmondroyd in https://github.com/handley-lab/anesthetic/pull/361</li> </ul> <p><strong>Full Changelog</strong>: https:
Lukas Hergt, Ethan Carragher, Johannes Buchner, yallup, tobyLovick, Adam Ormondroyd, Lorena A. Barba, Thomas Gessey-Jones, Will Handley, Harry Bevins, Juanjo Bazán, martinit18, Dily Ong, Stefan Heimersheim   +13 more
core   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

handley-lab/anesthetic: v2.8.2

<h2>What's Changed</h2> <ul> <li>Pandas 2.2.0 by @AdamOrmondroyd in https://github.com/handley-lab/anesthetic/pull/359</li> </ul> <p><strong>Full Changelog</strong>: https://github.com/handley-lab ...
Lukas Hergt, Ethan Carragher, Johannes Buchner, yallup, tobyLovick, Adam Ormondroyd, Lorena A. Barba, Thomas Gessey-Jones, Will Handley, Harry Bevins, Juanjo Bazán, martinit18, Dily Ong, Stefan Heimersheim   +13 more
core   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Lipid Emulsion Therapy as Treatment for Local Anesthetic Systemic Toxicity [PDF]

, 2011
Local anesthetic systemic toxicity, due to misapplication of local anesthetic in an otherwise routine procedure, can result in deleterious effects. Although improved regional anesthesia techniques, effective test-dosing, and availability of less toxic ...
Wentz, Nina R.
core   +1 more source

Sudden Severe Hypotension After Ultrasound Guided Femoral Nerve Block in a Fracture Neck Femur Patient: A Case Report

Clinical Case Reports
Local anesthetic systemic toxicity or hematomas are speculated as reasons for hemodynamic collapse after femoral block, which can be avoided by ultrasound guidance.
Omar Faiz Al Mohamadamin, Bhavsar Rajesh Prabhakar, Thomas Stroem   +2 more
doaj   +1 more source