Results 191 to 200 of about 87,448 (263)

Targeting DNGR‐1 with Fangchinoline Elevates Dendritic Cell Antigen Cross‐Presentation‐Mediated Antitumor Immunity in Melanoma

Advanced Science, EarlyView.
Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao, Zhenyang Ren, Jing Zhou, He Luo, Yuling Li, Dan Chen, Yuxiao Jiang, Canzhe Li, Mengyi Zheng, Anqi Li, Yao Wang, Yang Zhang, Dingye Wang, Yanjun Jiang, Jiangyong Gu, Biaoyan Du, Yafei Shi, Fang Liu, Jianyong Xiao, Kun Wang   +19 more
wiley   +1 more source

Laparoscopic-assisted transversus abdominus plane block versus intraperitoneal irrigation of local anesthetic for patients undergoing laparoscopic cholecystectomy: a prospective, multicentre, single-blinded, randomised controlled trial. [PDF]

Surg Endosc
Davey MG, Kearney DE, El-Masry S, Hill ADK, TAP CHOLE Trial Collaborators.   +4 more
europepmc   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

A promising novel local anesthetic for effective anesthesia in oral inflammatory conditions through reducing mitochondria-related apoptosis. [PDF]

Acta Pharm Sin B
Wang H, Hao Y, Gai W, Hu S, Liu W, Ma B, Shi R, Tan Y, Kang T, Hai A, Zhao Y, Tang Y, Ye L, Liu J, Liang X, Ke B.   +15 more
europepmc   +1 more source

Evaluating the interaction of local anesthetic agents with sequential and continuous chelation in root dentin - An <i>in vitro</i> study. [PDF]

J Conserv Dent Endod
Govindaraju L, Gnanasekaran S, Rajendran MR.   +2 more
europepmc   +1 more source

Management of Benign Findings Following Local Anesthetic Transperineal Prostate Biopsy: A Single-Center Review and Comparison With Current Guidelines. [PDF]

Cureus
Ali M, Thomas M, Morton J, Shafiq M, Adeniyi S, Sanan M, Lim PJ, Dyal A, Gallagher W, Koo V.   +9 more
europepmc   +1 more source

Different local anesthetic volumes in pericapsular nerve group block for hip fracture patients. [PDF]

Turk J Med Sci
Özgüner Y, Altinsoy S, Kültüroğlu G, Gürpinar SG, Özkan D, Ergil J, Aydin E.   +6 more
europepmc   +1 more source

Alkamides in Zanthoxylum Species: Phytochemical Profiles and Local Anesthetic Activities. [PDF]

Int J Mol Sci
Lu IC, Hu PY, Lin CH, Chang LL, Wang HC, Cheng KI, Gau TP, Lin KW.   +7 more
europepmc   +1 more source

Superficial Versus Deep Local Anesthetic Infiltration in Carpal Tunnel Release: A Randomized Clinical Trial. [PDF]

J Hand Surg Glob Online
Billard K, Cheng Y, Sims L, Sauder D.
europepmc   +1 more source