Results 231 to 240 of about 164,881 (359)

Feasibility of Percutaneous Gastrostomy Tube Placement Using Only Local Anesthetic in Patients With Neuromuscular Dysfunction [PDF]

S. Shanmugasundaram, Nardine Mikhail, Tarek Jazmati, Abhishek Kumar, Pratik A. Shukla   +4 more
openalex   +1 more source

The effects of rapid increases in desflurane and sevoflurane concentrations on spirometry in humans during balanced anesthesia with remifentanil [PDF]

, 2008
De Baerdemaeker, Luc, Kalmar, Alain, Struys, Michel, Willems, A   +3 more
core   +2 more sources

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

A promising novel local anesthetic for effective anesthesia in oral inflammatory conditions through reducing mitochondria-related apoptosis. [PDF]

Acta Pharm Sin B
Wang H, Hao Y, Gai W, Hu S, Liu W, Ma B, Shi R, Tan Y, Kang T, Hai A, Zhao Y, Tang Y, Ye L, Liu J, Liang X, Ke B.   +15 more
europepmc   +1 more source

Combined low dose local anesthetics and opioids versus single use of LA for transurethral urological surgery: A meta-analysis

, 2015
Yifan Chi, Yu Ding, Ming Li, Li Chen, Qian Zhang, An Jiang   +5 more
openalex   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Management of Benign Findings Following Local Anesthetic Transperineal Prostate Biopsy: A Single-Center Review and Comparison With Current Guidelines. [PDF]

Cureus
Ali M, Thomas M, Morton J, Shafiq M, Adeniyi S, Sanan M, Lim PJ, Dyal A, Gallagher W, Koo V.   +9 more
europepmc   +1 more source

Performance of 3 Conversational Generative Artificial Intelligence Models for Computing Maximum Safe Doses of Local Anesthetics: Comparative Analysis

Mélanie Suppan, Pietro Elias Fubini, Alexandra Stefani, Mia Gisselbaek, Caroline Samer, Georges L. Savoldelli   +5 more
openalex   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Evaluating the interaction of local anesthetic agents with sequential and continuous chelation in root dentin - An <i>in vitro</i> study. [PDF]

J Conserv Dent Endod
Govindaraju L, Gnanasekaran S, Rajendran MR.   +2 more
europepmc   +1 more source