Results 181 to 190 of about 5,940,795 (249)

Effect of Local Anesthetics on Experimental Postoperative Adhesion: A Systematic Review and Meta-Analysis with Trial Sequential Analysis. [PDF]

Medicina (Kaunas)
Lee JH, Lee D, Kang H.
europepmc   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Immediate-type allergic reactions to local anesthetics

Allergology International, 2018
Naomi Nakamura, Risa Tamagawa-Mineoka, Koji Masuda, Norito Katoh   +3 more
doaj   +1 more source

Topical local anesthetics for pain control at split-thickness skin graft donor sites in burn patients: a systematic review and meta-analysis of randomized controlled trials. [PDF]

BMC Anesthesiol
Jin W, Zhang L, Dong F, Li Y.
europepmc   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Brush-like Polymer Surface on Silk Fibroin Films for Controlled Release of Local Anesthetics. [PDF]

ACS Appl Mater Interfaces
Patil SA, Chen L, Foster C, Lin X, Xiao Y, Lu X, Feng B, Rowe CK, Burke KA.   +8 more
europepmc   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Dexmedetomidine as an adjunct to local anesthetics for impacted third molar surgery: a systematic review and meta-analysis. [PDF]

J Dent Anesth Pain Med
Alkabazi M, Aldieb E, Hussein H, Haridoss S, Tassoker M, Fernandes GVO.   +5 more
europepmc   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

Advanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li, Runzhe Huang, Qingyuan Wu, Pengbo Zhou, Dangli Ren, Jingjing Wang, Hanjie Niu, Zemeng Li, Hongtao Sun, Huiyu Liu   +9 more
wiley   +1 more source

Wound infiltration with local anesthetics during cesarean delivery with intrathecal opioids: A systematic review and meta-analysis of randomized control trials. [PDF]

Pregnancy (Hoboken)
Frusone V, Khanuja K, Sinnott J, Bellussi V, Ducarme G, Gomez-Rios M, Rosetti J, Roman A, Berghella V.   +8 more
europepmc   +1 more source