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Alkalinization of Local Anesthetics: Which Block, Which Local Anesthetic?
Regional Anesthesia: The Journal of Neural Blockade in Obstetrics, Surgery, & Pain Control, 1995Background and Objectives. A number of clinical studies have been performed in an attempt to establish the effects of alkalinization on potency of local anesthetics. Conflicting results were obtained probably because different studies used different methods as well as different definitions of the effects.
G, Capogna +3 more
openaire +2 more sources
The Journal of the American Dental Association, 2013
Francis V. Salinas, David B. Auyong
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Francis V. Salinas, David B. Auyong
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Local Anesthetics: Eutectic Mixture of Local Anesthetics
1991All commonly available local anesthetics have poor skin penetration when applied topically. One of the main reasons is that a local anesthetic agent needs to be in its cationic form in order to block nerve conduction. But it is the uncharged base which penetrates and diffuses into the tissues after topical administration.
openaire +1 more source
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Ca-A Cancer Journal for Clinicians, 2020Aaron J Grossberg +2 more
exaly