Results 51 to 60 of about 47,127 (296)
Arthritis Care &Research, EarlyView.Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source
Micro and nanosystems for delivering local anesthetics.
, 2015 One of the most common strategies for pain control during and after surgical procedures is the use of local anesthetics. Prolonged analgesia can be safely achieved with drug delivery systems suitably chosen for each local anesthetic agent.
Tofoli, Giovana R. +8 more
core +2 more sources
Local anesthetics and their adjuncts [PDF]
Pediatric Anesthesia, 2011 SummaryLocal anesthetics (LA) block propagation of impulses along nerve fibers by inactivation of voltage‐gated sodium channels, which initiate action potentials (1). They act on the cytosolic side of phospholipid membranes. Two main chemical compounds are used, amino esters and amino amides. Amino esters are degraded by pseudocholinesterases in plasma.
openaire +2 more sources
, 2023 There is considerable interest in the influence of anesthetic technique and/or perioperative analgesia on outcomes following surgical tumor excision. While the current clinical evidence is mixed, most clinical studies are predicated on the effects of ...
Hales, Tim G.; id_orcid +1 more
core +1 more source
Associations of Sleep and Shift Work With Osteoarthritis Risk
Arthritis Care &Research, EarlyView.Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik +5 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier +12 more
wiley +1 more source
Journal of Pain Research, 2021 Li Zhang,1,* Yirui Hu,2,* Xianren Wu,1 Michael J Paglia,3 Xiaopeng Zhang1 1Department of Anesthesiology, Geisinger Medical Center, Danville, PA, USA; 2Population Health Sciences, Geisinger Medical Center, Danville, PA, USA; 3Department of Obstetrics and ...
Zhang L, Hu Y, Wu X, Paglia MJ, Zhang X
doaj
Local anesthetics have been used as therapeutic agents for well over 100 years. The primary effects of local anesthetics occur at the site of administration by inhibiting the propagation of action potentials in sensory neurons. In medical practice today,
Edwards, Joshua +2 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper +7 more
wiley +1 more source
"Lidocaine anaphylaxis after epidural anesthesia for cesarean section " [PDF]
Acta Medica Iranica, 2001 Allergic reaction to local anesthetics is very rare and most of the reported cases are due to ester local anesthetics. This case presents a parturient who experienced cardiac arrest due to hypersensitivity reaction to lidocaine after epidural injection ...
Setayesh AR
doaj +1 more source