Results 41 to 50 of about 445,597 (304)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
BackgroundIn 2017 the SURG-Africa project set out to institute a surgical, obstetric, trauma and anesthesia (SOTA) care capacity-building intervention focused on non-specialist providers at district hospitals in Zambia, Malawi and Tanzania.
Chiara Pittalis +11 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Survey on and Countermeasures for Chemical Pollution of Water Used in Large Hotels: a Case Study
Water for hotel use mainly includes air conditioning circulating water and shower water. This paper conducts a survey on the current status of chemically polluted water in hotels in some area and analyses relevant countermeasures, hoping to give an ...
Shiying Yang, Hongfang Tian, Jingna Shi
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The subject of trust in public-state interactions and local self-government is examined using the example of agrarian protests on Zolsky pastures grasslands in Nalchik district in June 1913.
Dmitry Nikolaevich Prasolov
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Transparency of the budget process as a prerequisite for financial decentralization in Ukraine [PDF]
The introduction of a qualitatively new type of relationship between citizens and authorities, one in which every person would be guaranteed real observation and protection of the rights and freedoms in these bodies activity, should be one of the ...
Inna Shkolnyk +2 more
doaj +1 more source
The emergence of labour camps in Shandong province, 1942-1950 [PDF]
This article analyses the emergence of labour camps in the CCP base area of Shandong province from 1942 to 1950. By using original archival material, it provides a detailed understanding of the concrete workings of the penal system in a specific region ...
Dikötter, Frank
core +1 more source

