Results 71 to 80 of about 445,597 (304)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Yustisia, 2017 In this study, there are two (2) issues that were examined. First, how the Central Government and Local Government gained authority in the land sector.
Nurus Zaman
doaj +1 more source
Analisis Pelaksanaan Pengawasan Inspektorat Daerah terhadap Kinerja Badan Kepegawaian Daerah Kota Baubau [PDF]
, 2012 : This journal describes about the regional inspectorate supervision of the performance of local staffing agencies Baubau City. Inspectorate of Baubau an internal watchdog agency local governments have duties overseeing the regional government on the ...
Alam, A. S. (Andi) +2 more
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
THE FEATURES OF LEGAL REGULATION OF LEVI JEW’S BOX TAX IN BAKHCHISARAY CITY (1877-1881) [PDF]
Legal BulletinIn the article based on archive sources and legislation studying the features of legal regulation of special local duty - levi jew’s box tax at the end of XIX cent. in the period of local government reform in Bakhchisaray city where I.
VANIEV E.S.
doaj +1 more source
, 2013 This guideline relating to cover for the absence of the LSAMO for annual leave covers the period from 2012-2015.The policy sets out the arrangements to be put in place for cover for the LSAMO role and the contact details.
openaire +2 more sources
Organizational choices of banks and the effective supervision of transnational financial institutions : [Version: 19 Juli 2012] [PDF]
, 2012 This paper outlines relatively easy to implement reforms for the supervision of transnational banking-groups in the E.U. that should not be primarily based on legal form but on the actual risk structures of the pertinent financial institutions.
Tröger, Tobias
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Systemic oversight frameworks in LAC : current practices and reform agenda [PDF]
The world financial crisis that started in the US housing market in 2008 brought into evidence deep failures of prudential oversight, linked for the most part to a failure to comprehend and handle systemic risk in a way that could prevent systemic crises.
Caraballo, Patricia, Gutierrez, Eva
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source