Results 91 to 100 of about 2,111,359 (357)

DELIMITATION OF POWERS AND EXPENDITURE OBLIGATIONS OF STATE AUTHORITIES OF THE CONSTITUENT ENTITIES OF THE RUSSIAN FEDERATION AND LOCAL SELF-GOVERNMENT BODIES

, 2020
Alexey A. Sergeev
openalex   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Responding to unaccompanied minors in Scotland:policy and local authority perspectives [PDF]

, 2018
Following the provisions of the 2016 Immigration Act to permit the transfer of unaccompanied children the Scottish Government, COSLA, and local authorities have entered into negotiations with the Home Office to facilitate the arrival of children and ...
Fotopolou, Maria, Manta, Andriana, Rigby, Paul, Rogers, Ashley   +3 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Health Emergency Management in Public Administration: A Reproducible Model to Ensure Environmental Sustainability and Quality of the Spaces for Workers

Safety and Health at Work, 2022
Francesca Troiano, Giuseppe Furia, Carmela Puleo, Patrizia Chierchini, Anna Zoppegno, Maddalena Quintili   +5 more
doaj   +1 more source

Gender differences, environmental pressures, tumor characteristics, and death rate in a lung cancer cohort: a seven-years Bayesian survival analysis using cancer registry data from a contaminated area in Italy

Frontiers in Public Health
IntroductionIn Taranto, Southern Italy, adverse impacts on the environment and human health due to industrial installations have been studied. In the literature, associations have been reported between gender, environmental factors, and lung cancer ...
Antonia Mincuzzi, Simona Carone, Claudia Galluzzo, Margherita Tanzarella, Giovanna Maria Lagravinese, Antonella Bruni, Ivan Rashid, Lucia Bisceglia, Rodolfo Sardone, Francesco Addabbo, Sante Minerba, Orazio Valerio Giannico   +11 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Environmental pressures, tumor characteristics, and death rate in a female breast cancer cohort: a seven-years Bayesian survival analysis using cancer registry data from a contaminated area in Italy

Frontiers in Public Health
IntroductionIn Taranto, Southern Italy, adverse impacts on the environment and human health due to industrial installations have been studied. In the literature, few associations have been reported between environmental factors and breast cancer ...
Orazio Valerio Giannico, Simona Carone, Margherita Tanzarella, Claudia Galluzzo, Antonella Bruni, Giovanna Maria Lagravinese, Ivan Rashid, Lucia Bisceglia, Rodolfo Sardone, Francesco Addabbo, Sante Minerba, Antonia Mincuzzi   +11 more
doaj   +1 more source

Architectural Design Quality in Local Authority Private Finance Initiative Projects [PDF]

, 2010
Since the 1990s, when the Private Finance Initiative was developed as the primary method for delivering major public capital projects, there has been concern about the quality of many of the products.
Giddings, Bob, Jensen, Phil, Jones, Paul, Sharma, Monika   +3 more
core