Results 121 to 130 of about 2,111,359 (357)

THE DEVELOPMENT OF POLICIES AND TRENDS REGARDING SERVICE PROVISION AGREEMENTS BETWEEN LOCAL AUTHORITIES AND BUS OPERATORS IN THE U.K.

, 2023
Ryusuke TAKEUCHI, Fumihiko Nakamura, Shinji TSURUSASHI, Soichiro Minami   +3 more
openalex   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Framing the wider determinants of health: Reflections and learning from a knowledge mobilisation exercise with an English local authority. [PDF]

Public Health Pract (Oxf), 2023
Such E, Akakpo D, Cleghorn L, Eddleston F, Eyoma J, Fish L, Jan-Khan M, Khattran S, Leitner V, Young C, Laurent C.   +10 more
europepmc   +1 more source

1+2 Languages Implementation: Findings from the 2019 local authority survey [PDF]

, 2020

core  

Authority of State and Local Police to Enforce Federal Immigration Law [PDF]

, 2010
[Excerpt] This report discusses the authority of state and local law enforcement to assist in the enforcement of federal immigration law through the investigation and arrest of persons believed to have violated such laws.
Garcia, Michael J, Manuel, Kate M
core   +6 more sources

A framework for assessing the contribution of UK local authorities toward compliance with the EU ambient air quality directive [PDF]

, 2021
Katherine Fremantle, Laura De Vito, Ben Williams, James Longhurst   +3 more
openalex   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Enhancing the training of community engagement officers to address vaccine hesitancy: a university and local authority collaboration. [PDF]

Perspect Public Health, 2023
Murdan S, Ali N, Darlow J, Christopher E, Tolani F, Ashiru-Oredope D.   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Integrated working in local authority decision-making about air quality: a qualitative study in Southwest England. [PDF]

J Public Health (Oxf), 2023
Turner A, Webb A, Jago R, Blackmore S, de Vocht F, Horwood J.   +5 more
europepmc   +1 more source