Results 51 to 60 of about 5,962,372 (294)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pembagian Kewenangan dalam Pelayanan Publik antara Pemerintah Pusat dan Pemerintah Daerah

open access: yesJKAP (Jurnal Kebijakan dan Administrasi Publik), 2015
The implementation of new laws on local autonomy in Indonesia has arisen hopes democracy an better services at the local level. However, these no hopes have not materialized as yer due to various barriers.
Erwan Agus Purwanto
doaj   +1 more source

LOCAL AUTHORITIES’ ECONOMIC ATTRIBUTIONS IN THE LIGHT OF THE ROMANIAN ADMINISTRATIVE CODE [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2021
This study presents the newest legislative regulations regarding the financial and economic attributions of the Romanian administrative local authorities.
MELINDA CENUŞE
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

NUEVAS FORMAS DE PARTICIPACIÓN DE LOS ENTES LOCALES: EL CONSEJO DE GOBIERNOS LOCALES [PDF]

open access: yesRevista d'Estudis Autonòmics i Federals, 2006
The proposal for the reform of the Statute of Autonomy of Catalonia waspassed by the Catalan Parliament on September 2005. Besides the improvementof self-government of Catalonia, the proposal also tries to define the Catalonia’slocal institutional system,
Marc Vilalta Reixach
doaj  

Capital Cities in Interurban Competition: Local Autonomy, Urban Governance, and Locational Policy Making

open access: yesUrban Affairs Review, 2018
Capital cities are government cities that tend to lack a competitive political economy. Especially secondary capital cities—defined as capitals that are not the primary economic centers of their nation-states—are pressured to increase their economic ...
David Kaufmann
semanticscholar   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Financial Autonomy of Municipalities – Microeconomic Backgrounds [PDF]

open access: yesSocietas et Iurisprudentia, 2016
Financial autonomy is an important aspect of the local government existence. In the paper there is analysed a sample of the Slovak municipalities on which a modified methodology of quantification of municipal financial autonomy has been applied. The same
Ladislav Poliak
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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