Results 61 to 70 of about 1,356,854 (269)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Value-Oriented English Learning Materials: A Conceptual Review of Textbooks, Local Content, and Character Education

open access: yesJournal of English Language Teaching and Literature
This study explores the role of value-oriented English textbooks in connecting language learning with moral, cultural, and character education values. In many Indonesian classrooms, commercial textbooks dominate and often fail to represent local contexts
Akhmad Ghifari   +3 more
doaj   +1 more source

Identifikasi Kuliner Lokal Indonesia dalam Pembelajaran Bahasa Inggris

open access: yesJurnal Pariwisata Terapan, 2017
This study is aimed at identifying the representation of local foods and beverages in English textbooks used in Indonesia. Based on the current curriculum, character building should be promoted as one of the learning goals. This effort is to maintain and
Agnes Siwi Purwaning Tyas
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Penerapan Material Bahan Bangunan dan Konsep Pemaknaan pada Gereja Puh Sarang sebagai Warisan Budaya Indonesia

open access: yesHumaniora, 2011
Puh Sarang Church which located at Kediri, East Java, Indonesia, who’s made by Henri Maclaine Pont, give an illustrated of case study, how the Church developed with a good and great idea from the Architect which his effort to revitalized a local mind (
Grace Hartanti
doaj  

Implementasi Kurikulum Muatan Lokal PAI Tingkat SMP di Kabupaten Bangka Tengah Kepulauan Bangka Belitung

open access: yesNadwa, 2015
The purpose of this study is to determine the policies to address the problem PAI, a strategy to overcome the schedule of PAI, and models of a local curriculum (PAI) in Central Bangka Regency.
Suparta
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Local content of bipartite qubit correlations

open access: yesPhysical Review A, 2010
One of the last open problems concerning two qubits in a pure state is to find the exact local content of their correlation, in the sense of Elitzur, Popescu and Rohrlich (EPR2) [Phys. Lett. A 162, 25 (1992)]. We propose a new EPR2 decomposition that allows us to prove, for a wide range of states psi(theta)=cos(theta)|00>+sin(theta)|11>, that ...
Branciard, Cyril   +2 more
openaire   +7 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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