Results 101 to 110 of about 1,356,854 (269)
ANALISIS EFEKTIVITAS IKLAN-IKLAN TV BERTEMA LOCAL CONTENT DI INDONESIA TAHUN 2004
In the globalization era, local content TV commercials are considered to be more and more important. This thesis aims to analyze how far the local content TV commercials can be accepted by the Indonesian audience, who are culturally diverse; moreover ...
Bernadette Dian Arini Maer +2 more
doaj
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
A conceptual model for local content development in petroleum industry [PDF]
A novel concept, local content, in oil industry is gradually emerging. Local content should be defined in terms of value addition in local country (by local staff, local materials, local services and facilities) rather than in terms of ownership of the ...
Abolfazl Kazzazi, Behrouz Nouri
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Managing Local Wisdom-Based Curriculum: An Integrative Framework for Madrasah Education
This study aims to analyze and develop a curriculum model grounded in local wisdom for madrasas. The study focuses on curriculum planning, implementation, and evaluation, as well as a comparison of implementation across two madrasas.
Cut Irhamna Heriyanti +2 more
doaj +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Conscious Vision Proceeds from Global to Local Content in Goal-Directed Tasks and Spontaneous Vision. [PDF]
Campana F +4 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source

